Molecular structure of Prostaglandin E2 methyl ester, CAS Number: 31753-17-0
Prostaglandin E2 methyl ester (CAS 31753-17-0)
Alternate Names:
PGE2 methyl ester
Application:
Prostaglandin E2 methyl ester is an analog of PGE2 that is believed to be involved with rapid-eye-movement sleep regulation
CAS Number:
31753-17-0
Molecular Weight:
366.5
Molecular Formula:
C21H34O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Prostaglandin E2 methyl ester is an analog of PGE2 (sc-201225) with enhanced lipid solubility, that has been suggested to play a role in rapid-eye-movement sleep regulation. PGE2 is the most physiologically abundant eicosanoid, which is produced predominantly from arachidonic acid (sc-200770) by COX and PGE2, and exists at some level in nearly all cell types. PGE2 acts on four different receptors termed EP1 through EP4 yielding an astounding array of biological effects; the use of these prostaglandin analogues is integral for structure-activity studies used in the deconvolution of these complex biochemical pathways.
Prostaglandin E,[object Object], methyl ester (CAS 31753-17-0) References
- Detection of the 15-acetate of prostaglandin E2 methyl ester as a prominent component of the prostaglandins in the gorgonian coral Plexaura homomalla. | Schneider, C., et al. 2002. Lipids. 37: 217-21. PMID: 11908914
- Actions of prostanoids to induce emesis and defecation in the ferret. | Kan, KK., et al. 2002. Eur J Pharmacol. 453: 299-308. PMID: 12398918
- Multicomponent Strategy for the Synthesis of Prostaglandin E2 Methyl Ester under Anion Relay Chelation Control. | Huang, KH., et al. 2016. J Org Chem. 81: 1571-84. PMID: 26811990
- Prostaglandin E2 and its methyl ester reduce cataplexy in canine narcolepsy. | Nishino, S., et al. 1989. Proc Natl Acad Sci U S A. 86: 2483-7. PMID: 2928344
- Effects of 15(S)-15-methyl prostaglandin E2 methyl ester on phospholipid metabolism in rat gastric mucosa. | Nishizawa, Y. and Moriga, M. 1989. Biochem Pharmacol. 38: 955-60. PMID: 2930596
- Effect of 16,16-dimethyl prostaglandin E2 methyl ester on weanling rat skeleton: daily and systemic administration. | Furuta, Y. and Jee, WS. 1986. Anat Rec. 215: 305-16. PMID: 3740468
- Gastric antisecretory actions of (15S)-15-methyl prostaglandin E2 methyl ester and natural prostaglandin E2 in rhesus monkeys. | Dajani, EZ. and Callison, DA. 1976. Prostaglandins. 11: 799-808. PMID: 819967
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Prostaglandin E2 methyl ester, 500 µg | sc-224220 | 500 µg | $27.00 | |||
Prostaglandin E2 methyl ester, 1 mg | sc-224220A | 1 mg | $50.00 |