Molecular structure of Prostaglandin E1 Alcohol, CAS Number: 21562-57-2
Prostaglandin E1 Alcohol (CAS 21562-57-2)
Alternate Names:
PGE1 Alcohol; 1,11α,15S-trihydroxy-prost-13E-en-9-one
Application:
Prostaglandin E1 Alcohol is a non-irritant bronchodilator
CAS Number:
21562-57-2
Molecular Weight:
340.50
Molecular Formula:
C20H36O4
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
PGE1 alcohol is a non-irritant bronchodilator, with relaxant activity on the human bronchial muscle in vitro, comparable to PGE1 at concentrations of 0.01 to 10.0 µg/ml.1,2 PGE1 alcohol binds to the mouse recombinant EP3 and EP4 receptors with Ki values of 330 and 190 nM, respectively.3 Asthmatics receiving single dose inhalation treatments reported significant but short-acting bronchodilation at doses of 10 and 30 µg.1
Prostaglandin E1 Alcohol (CAS 21562-57-2) References
- Bronchodilatory properties of 2-decarboxy-2-hydroxymethyl prostaglandin E1. | Nizankowska, E., et al. 1985. Prostaglandins. 29: 349-62. PMID: 3858912
- 2-decarboxy-2-hydroxymethyl prostaglandin E1 (TR4161), a prostaglandin bronchodilator of low tracheobronchial irritancy. | Gardiner, PJ., et al. 1980. Prostaglandins. 19: 349-70. PMID: 7384544
- Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells. | Kiriyama, M., et al. 1997. Br J Pharmacol. 122: 217-24. PMID: 9313928
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Prostaglandin E1 Alcohol, 500 µg | sc-224219 | 500 µg | $34.00 | |||
Prostaglandin E1 Alcohol, 1 mg | sc-224219A | 1 mg | $65.00 |