Molecular structure of Prostaglandin D2 Ethanolamide, CAS Number: 398138-28-8
Prostaglandin D2 Ethanolamide (CAS 398138-28-8)
Alternate Names:
PGD2-EA; Prostamide D2
Application:
Prostaglandin D2 Ethanolamide is a PGD2 analog formed via Anandamide which acts as a substrate for cyclooxygenase
CAS Number:
398138-28-8
Molecular Weight:
395.54
Molecular Formula:
C22H37NO5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Prostaglandin D2 Ethanolamide is a PGD2 (sc-201221) analog formed via Anandamide (Arachinodoyl Ethanolamine; AEA; sc-200790), which acts as a substrate for cyclooxygenase. The conversion of AEA to prostaglandins has been demonstrated with many different eicosanoids, some of which display unique biological activity. The use of these prostaglandin analogues is integral for structure-activity studies used in the deconvolution of these complex biochemical pathways.
Prostaglandin D2 Ethanolamide (CAS 398138-28-8) References
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- Formation of prostamides from anandamide in FAAH knockout mice analyzed by HPLC with tandem mass spectrometry. | Weber, A., et al. 2004. J Lipid Res. 45: 757-63. PMID: 14729864
- Cyclooxygenation of the arachidonoyl side chain of 1-arachidonoylglycerol and related compounds block their ability to prevent anandamide and 2-oleoylglycerol metabolism by rat brain in vitro. | Fowler, CJ. and Tiger, G. 2005. Biochem Pharmacol. 69: 1241-5. PMID: 15794945
- The multiple pathways of endocannabinoid metabolism: a zoom out. | Vandevoorde, S. and Lambert, DM. 2007. Chem Biodivers. 4: 1858-81. PMID: 17712823
- High-throughput lipidomic analysis of fatty acid derived eicosanoids and N-acylethanolamines. | Dumlao, DS., et al. 2011. Biochim Biophys Acta. 1811: 724-36. PMID: 21689782
- Enzymes of the cyclooxygenase pathways of prostanoid biosynthesis. | Smith, WL., et al. 2011. Chem Rev. 111: 5821-65. PMID: 21942677
- Meat, the metabolites: an integrated metabolite profiling and lipidomics approach for the detection of the adulteration of beef with pork. | Trivedi, DK., et al. 2016. Analyst. 141: 2155-64. PMID: 26911805
- Prostaglandin D2-ethanolamide induces skin cancer apoptosis by suppressing the activity of cellular antioxidants. | Elhassanny, AEM., et al. 2019. Prostaglandins Other Lipid Mediat. 142: 9-23. PMID: 30858059
- Apoptosis mechanisms induced by 15d-PMJ2 in HCT116 colon cancer cells: insights into CHOP10/TRB3/Akt signaling. | Albassam, H., et al. 2023. Front Pharmacol. 14: 1283677. PMID: 38026967
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Prostaglandin D2 Ethanolamide, 1 mg | sc-205447 | 1 mg | $88.00 | |||
Prostaglandin D2 Ethanolamide, 5 mg | sc-205447A | 5 mg | $395.00 |