Date published: 2026-4-20

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Prostaglandin D1 (CAS 17968-82-0)

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Alternate Names:
PGD1
Application:
Prostaglandin D1 is a relatively weak inhibitor of ADP-induced platelet aggregation
CAS Number:
17968-82-0
Molecular Weight:
354.5
Molecular Formula:
C20H34O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Prostaglandin D1 (PGD1) is a lipid compound that has attention in biochemistry and immunology research due to its role as an eicosanoid signaling molecule. It′s involved in a myriad of physiological processes, including the modulation of inflammation, platelet aggregation, and vasodilation. Research involving Prostaglandin D1 frequently focuses on its synthesis and metabolism, as well as its interactions with specific prostaglandin receptors, which can elucidate its function in both normal and pathological states. In the context of inflammation, Prostaglandin D1 studies help to understand its contrasting roles, as it can both promote and resolve cellular inflammatory responses under different conditions. It′s also a subject in the study of sleep-wake regulation.


Prostaglandin D1 (CAS 17968-82-0) References

  1. Proceedings: Prostaglandin D1 inhibits the increase in vascular permeability in rat skin produced by prostaglandin E1, E2 and D2.  |  Flower, RJ. and Kingston, WP. 1975. Br J Pharmacol. 55: 239P-240P. PMID: 1201383
  2. Dihomo-γ-linolenic acid prevents the development of atopic dermatitis through prostaglandin D1 production in NC/Tnd mice.  |  Amagai, Y., et al. 2015. J Dermatol Sci. 79: 30-7. PMID: 25907057
  3. Simultaneous LC-MS/MS analysis of eicosanoids and related metabolites in human serum, sputum and BALF.  |  Thakare, R., et al. 2018. Biomed Chromatogr. 32: PMID: 28975688
  4. A single meal has the potential to alter brain oxylipin content.  |  Norman, JE., et al. 2020. Prostaglandins Leukot Essent Fatty Acids. 154: 102062. PMID: 32062416
  5. Development of a radioimmunoassay for prostaglandin D2 using an antiserum against 11-methoxime prostaglandin D2.  |  Maclouf, J., et al. 1986. Prostaglandins. 31: 123-32. PMID: 3456623
  6. Study on the Molecular Basis of Huanglian Jiedu Decoction Against Atopic Dermatitis Integrating Chemistry, Biochemistry, and Metabolomics Strategies.  |  Chen, J., et al. 2021. Front Pharmacol. 12: 770524. PMID: 34970141
  7. Eicosanoids in inflammation in the blood and the vessel.  |  Yamaguchi, A., et al. 2022. Front Pharmacol. 13: 997403. PMID: 36238558
  8. Role of Oxylipins in the Inflammatory-Related Diseases NAFLD, Obesity, and Type 2 Diabetes.  |  Misheva, M., et al. 2022. Metabolites. 12: PMID: 36557276
  9. Acute and Rapid Response of Melissa officinalis and Mentha spicata to Saline Reclaimed Water in Terms of Water Relations, Hormones, Amino Acids and Plant Oxylipins.  |  Gómez-Bellot, MJ., et al. 2022. Plants (Basel). 11: PMID: 36559540
  10. Isolation and properties of intermediates in prostaglandin biosynthesis.  |  Nugteren, DH. and Hazelhof, E. 1973. Biochim Biophys Acta. 326: 448-61. PMID: 4776443
  11. Synthesis and platelet aggregation inhibiting activity of prostaglandin D analogues.  |  Bundy, GL., et al. 1983. J Med Chem. 26: 790-9. PMID: 6854581
  12. Metabolism of 8,11,14-eicosatrienoic acid in human platelets.  |  Falardeau, P., et al. 1976. Biochim Biophys Acta. 441: 193-200. PMID: 952987
  13. Synthesis of prostaglandin D1 and D2 via the three-component coupling process  |  Suzuki, M., Yanagisawa, A., & Noyori, R. 1984. Tetrahedron letters. 25(13): 1383-1386.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Prostaglandin D1, 1 mg

sc-205446
1 mg
$83.00

Prostaglandin D1, 5 mg

sc-205446A
5 mg
$392.00