Date published: 2026-4-25

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Propylene sulfide (CAS 1072-43-1)

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Alternate Names:
Methylethylene Sulfide; Methylthiirane
CAS Number:
1072-43-1
Molecular Weight:
74.14
Molecular Formula:
C3H6S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Propylene sulfide (PS) is an organic compound characterized as a colorless, volatile liquid with a slight garlic-like odor. Known for its flammability and reactivity, Propylene sulfide is broadly utilized in industrial applications and in the synthesis of diverse organic compounds. These include fragrances, dyes, food additives, biocides, and lubricants. The potential applications of Propylene sulfide extend to the biotechnology and food industries, triggering extensive scientific research. It has been investigated as a potential drug delivery system, a catalyst for organic reactions, a solvent for various organic compounds, and for its potential role in the production of biopolymers and nanomaterials. While the exact mechanism of action of propylene sulfide remains elusive, it′s postulated to operate as a Lewis acid catalyst, aiding the creation of covalent bonds among molecules. It′s also speculated to partake in the formation of hydrogen bonds, thereby enhancing the reactivity of certain compounds.


Propylene sulfide (CAS 1072-43-1) References

  1. Phototocatalytic lithography of poly(propylene sulfide) block copolymers: toward high-throughput nanolithography for biomolecular arraying applications.  |  Bearinger, JP., et al. 2009. Langmuir. 25: 1238-44. PMID: 19113808
  2. Hydrolase stabilization via entanglement in poly(propylene sulfide) nanoparticles: stability towards reactive oxygen species.  |  Allen, BL., et al. 2012. Nanotechnology. 23: 294009. PMID: 22743846
  3. End-group rearrangements in poly(propylene sulfide) matrix-assisted laser desorption/ionization time-of-flight analysis. Experimental evidence and possible mechanisms.  |  Lallana, E., et al. 2012. Rapid Commun Mass Spectrom. 26: 2158-64. PMID: 22886812
  4. Accelerated wound healing by injectable star poly(ethylene glycol)-b-poly(propylene sulfide) scaffolds loaded with poorly water-soluble drugs.  |  Zhu, S., et al. 2018. J Control Release. 282: 156-165. PMID: 29751029
  5. Ginsenoside Rg3-loaded, reactive oxygen species-responsive polymeric nanoparticles for alleviating myocardial ischemia-reperfusion injury.  |  Li, L., et al. 2020. J Control Release. 317: 259-272. PMID: 31783047
  6. Mapping the supramolecular assembly space of poly(sarcosine)-b-poly(propylene sulfide) using a combinatorial copolymer library.  |  Frey, M., et al. 2020. Chem Commun (Camb). 56: 6644-6647. PMID: 32406439

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Propylene sulfide, 5 ml

sc-487961A
5 ml
$92.00

Propylene sulfide, 25 ml

sc-487961
25 ml
$235.00