Date published: 2025-10-3

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Propylene Glycol (CAS 57-55-6)

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Alternate Names:
1,2-Propanediol
CAS Number:
57-55-6
Purity:
≥98%
Molecular Weight:
76.09
Molecular Formula:
C3H8O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Propylene glycol is a versatile compound widely utilized in various industrial and consumer goods. It is a colorless, odorless, and slightly viscous liquid that readily mixes with water. In biochemical and physiological research, propylene glycol finds extensive use as a solvent due to its non-toxic nature and low vapor pressure. It also serves as an effective cryoprotectant, safeguarding cells and tissues against the detrimental consequences of freezing. Furthermore, propylene glycol has proven valuable in investigations concerning drug absorption, metabolism, and distribution.


Propylene Glycol (CAS 57-55-6) References

  1. Propylene glycol accumulation in critically ill patients receiving continuous intravenous lorazepam infusions.  |  Horinek, EL., et al. 2009. Ann Pharmacother. 43: 1964-71. PMID: 19920159
  2. Propylene Glycol-Related Delirium After Esmolol Infusion.  |  Kapitein, B., et al. 2014. Ann Pharmacother. 48: 940-942. PMID: 24687543
  3. Bactericidal activity of propylene glycol, glycerine, polyethylene glycol 400, and polyethylene glycol 1000 against selected microorganisms.  |  Nalawade, TM., et al. 2015. J Int Soc Prev Community Dent. 5: 114-9. PMID: 25992336
  4. Propylene-glycol-induced pulmonary hypertension in sheep.  |  Pearl, RG. and Rice, SA. 1989. Pharmacology. 39: 383-9. PMID: 2634856
  5. Propylene Glycol Poisoning From Excess Whiskey Ingestion: A Case of High Osmolal Gap Metabolic Acidosis.  |  Cunningham, CA., et al. 2015. J Investig Med High Impact Case Rep. 3: 2324709615603722. PMID: 26904700
  6. Propylene Glycol Toxicity in Adolescent with Refractory Myoclonic Status Epilepticus.  |  Bjur, KA., et al. 2017. Case Rep Pediatr. 2017: 2979486. PMID: 28331645
  7. Chemosensory Event-Related Potentials in Response to Nasal Propylene Glycol Stimulation.  |  Sirous, M., et al. 2019. Front Hum Neurosci. 13: 99. PMID: 30949040
  8. Iatrogenic Propylene Glycol Intoxication Due to High-Dose Pentobarbital for Refractory Intracranial Hypertension: A Case Report.  |  Smedley, LW., et al. 2020. J Pharm Pract. 33: 895-898. PMID: 31238770
  9. Use of Propylene-Glycol as a Cosolvent for GnRH in Synchronization of Estrus and Ovulation in Sheep.  |  Santos-Jimenez, Z., et al. 2020. Animals (Basel). 10: PMID: 32455785
  10. Phytol, not propylene glycol, causes severe pulmonary injury after inhalation dosing in Sprague-Dawley rats.  |  Schwotzer, D., et al. 2021. Inhal Toxicol. 33: 33-40. PMID: 33441006
  11. Formation of Water-Channel by Propylene Glycol into Polymer for Porous Materials.  |  Hong, SH., et al. 2021. Membranes (Basel). 11: PMID: 34832110
  12. Hydrogenolysis of Glycerol to Propylene Glycol: Energy, Tech-Economic, and Environmental Studies.  |  Sun, P., et al. 2021. Front Chem. 9: 778579. PMID: 35127642
  13. Revisions to Limits for Propylene Glycol in Spacecraft Air.  |  Ryder, VE. and Williams, ES. 2022. Aerosp Med Hum Perform. 93: 467-469. PMID: 35551723
  14. Survivorship-Reducing Effect of Propylene Glycol on Vector Mosquito Populations and Its Potential Use in Attractive Toxic Sugar Baits.  |  Pullmann Lindsley, H., et al. 2022. Insects. 13: PMID: 35886771
  15. Unraveling propylene glycol-induced lipolysis of the biosynthesis pathway in ultra-high temperature milk using high resolution mass spectrometry untargeted lipidomics and proteomics.  |  Jia, W. and Di, C. 2023. Food Res Int. 164: 112459. PMID: 36738011

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Propylene Glycol, 500 ml

sc-215754
500 ml
$232.00

Propylene Glycol, 4 L

sc-215754A
4 L
$447.00