Propyl arachidonate (CAS 93913-74-7)

Propyl arachidonate, with the CAS number 93913-74-7, is an esterified form of arachidonic acid, a polyunsaturated omega-6 fatty acid that is a precursor in the biosynthesis of various eicosanoids. This compound features a propyl group esterified to the carboxyl end of arachidonic acid, altering its physical and chemical properties compared to its free acid form. In research, propyl arachidonate is prominently utilized as a standard and reagent in analytical studies involving lipidomics and fatty acid metabolism. Its ester form makes it more volatile and stable, facilitating its use in gas chromatography and mass spectrometry for the quantification and analysis of fatty acid compositions in biological samples. This is critical in studies aimed at understanding the role of fatty acids in cellular processes and their impact on cellular membrane dynamics and signaling pathways. Additionally, propyl arachidonate serves as a tool in the synthesis of labeled compounds where isotopically marked versions can be used to trace and study metabolic pathways of arachidonic acid derivatives, including prostaglandins and leukotrienes. By providing a means to explore these pathways, propyl arachidonate contributes significantly to the field of biochemical research, particularly in the study of inflammatory responses and signal transduction.