Propofol β-D-glucuronide CAS: 114991-26-3
MF: C18H26O7
MW: 354.39
A Propofol metabolite.

Propofol β-D-glucuronide (CAS 114991-26-3)

Propofol β-D-glucuronide | CAS 114991-26-3 is rated 5.0 out of 5 by 1.
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Alternate Names: 2,6-Bis(1-methylethyl)phenyll β-D-glucopyranosiduronic acid; Propofol Glucuronide
Application: Propofol β-D-glucuronide is a Propofol metabolite
CAS Number: 114991-26-3
Purity: ≥98%
Molecular Weight: 354.39
Molecular Formula: C18H26O7
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Propofol Glucuronide is a metabolite following rapid clearance of Propofol linked with glucuronidation by the uridine diphosphate glucuronosyltransferases. The compound has been used as a standard to develop a liquid chromatography and mass spectroscopy bioanalytical assay for in vitro enzyme kinetics and in vivo pharmacokinetics of of glucuronides.


References

1. Favetta, P., et al. 2002. Br J Anaesth. 88: 653-658. PMID: 12067002
2. Soars, M.G., et al. 2002. J Pharmacol Toxicol Methods. 47: 161-168. PMID: 12628307
3. Fujiwara, R., et al. 2007. Drug Metab. Dispos. 35: 747-757. PMID: 17293379

Physical State :
Solid
Solubility :
Soluble in DMSO, Ethanol and Methanol
Storage :
Store at -20° C
Melting Point :
142-143° C
Boiling Point :
~562.4° C at 760 mmHg (Predicted)
Density :
~1.3 g/cm3 (Predicted)
Refractive Index :
n20D 1.58 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
SMILES :
CC(C)C1=C(C(=CC=C1)C(C)C)O[[email protected]]2[[email protected]@H]([[email protected]]([[email protected]@H]([[email protected]](O2)C(=O)O)O)O)O

Download SDS (MSDS)

Certificate of Analysis

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Propofol β-D-glucuronide (CAS 114991-26-3)  Product Citations

See how others have used Propofol β-D-glucuronide (CAS 114991-26-3). Click on the entry to view the PubMed entry .

Citations 1 to 3 of 3 total

PMID: # 24470170  Yamamoto, K. et al. 2014. European journal of drug metabolism and pharmacokinetics. 39: 195-202.

PMID: # 25985579  Mukai, M. et al. 2014. Die Pharmazie. 69: 829-32.

PMID: # 23562620  Arch Biochem Biophys. 143-9.

Citations 1 to 3 of 3 total

What is the shipping temperature for this product?

Asked by: hawkeye11
This chemical, Propofol β-D-glucuronide (CAS 114991-26-3), ships ambient.
Answered by: Chemical Support 1
Date published: 2017-03-24
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Rated 5 out of 5 by from Various publications cite the use of Propofol Various publications cite the use of Propofol -D-glucuronide, a Propofol metabolite, as a standard in the development of a liquid chromatography and mass spectroscopy bioanalytical assay for in vitro enzyme kinetics and in vivo pharmacokinetics of of glucuronides. -SCBT Publication Review
Date published: 2015-01-02
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