Date published: 2026-4-4

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Propionic Acid (CAS 79-09-4)

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Alternate Names:
Propanoic Acid
CAS Number:
79-09-4
Purity:
≥98%
Molecular Weight:
74.08
Molecular Formula:
C3H6O2
Supplemental Information:
This is as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Propionic acid functions as a preservative in various experimental applications. It acts by inhibiting the growth of mold and bacteria, thereby extending the shelf life of products. At the molecular level, propionic acid disrupts the cellular processes of microorganisms, leading to their eventual death. Its mechanism of action involves penetrating the cell membrane of microorganisms and disrupting their metabolic pathways, ultimately leading to their demise.


Propionic Acid (CAS 79-09-4) References

  1. Production of acrylic acid and propionic acid by constructing a portion of the 3-hydroxypropionate/4-hydroxybutyrate cycle from Metallosphaera sedula in Escherichia coli.  |  Liu, Z. and Liu, T. 2016. J Ind Microbiol Biotechnol. 43: 1659-1670. PMID: 27722922
  2. Propionic Acid Promotes the Virulent Phenotype of Crohn's Disease-Associated Adherent-Invasive Escherichia coli.  |  Ormsby, MJ., et al. 2020. Cell Rep. 30: 2297-2305.e5. PMID: 32075765
  3. Simultaneous production of propionic acid and vitamin B12 from corn stalk hydrolysates by Propionibacterium freudenreichii in an expanded bed adsorption bioreactor.  |  Wang, P., et al. 2020. Prep Biochem Biotechnol. 50: 763-767. PMID: 32134358
  4. Reversibility of propionic acid inhibition to anaerobic digestion: Inhibition kinetics and microbial mechanism.  |  Han, Y., et al. 2020. Chemosphere. 255: 126840. PMID: 32387725
  5. Propionic acid induces dendritic spine loss by MAPK/ERK signaling and dysregulation of autophagic flux.  |  Choi, H., et al. 2020. Mol Brain. 13: 86. PMID: 32487196
  6. Propionic acid production from food waste in batch reactors: Effect of pH, types of inoculum, and thermal pre-treatment.  |  Ali, R., et al. 2021. Bioresour Technol. 319: 124166. PMID: 32992271
  7. Propionic acid production by Propionibacterium freudenreichii using sweet sorghum bagasse hydrolysate.  |  Ammar, EM., et al. 2020. Appl Microbiol Biotechnol. 104: 9619-9629. PMID: 33047167
  8. Propionic acid production from apple pomace in bioreactor using Propionibacterium freudenreichii: an economic analysis of the process.  |  Piwowarek, K., et al. 2021. 3 Biotech. 11: 60. PMID: 33489679
  9. Propionic acid disrupts endocytosis, cell cycle, and cellular respiration in yeast.  |  Micalizzi, EW., et al. 2021. BMC Res Notes. 14: 335. PMID: 34454571
  10. Propionic acid induces apoptosis-like death in Escherichia coli O157.  |  Kim, M. and Lee, DG. 2022. J Basic Microbiol. 62: 22-34. PMID: 34904256
  11. Quantitation of propionic acid in emmental cheese products by direct solvent extraction.  |  Oh, CH. and Jeong, HS. 2022. Food Sci Biotechnol. 31: 183-190. PMID: 35186348
  12. Gut Microflora Modulates Th17/Treg Cell Differentiation in Experimental Autoimmune Prostatitis via the Short-Chain Fatty Acid Propionate.  |  Du, HX., et al. 2022. Front Immunol. 13: 915218. PMID: 35860242
  13. Bioproduction of propionic acid using levulinic acid by engineered Pseudomonas putida.  |  Tiwari, R., et al. 2022. Front Bioeng Biotechnol. 10: 939248. PMID: 36032729
  14. Intestinal Microbiota-derived Propionic Acid Protects against Zinc Oxide Nanoparticle-induced Lung Injury.  |  Zhang, Y., et al. 2022. Am J Respir Cell Mol Biol. 67: 680-694. PMID: 36150095
  15. Lactobacillus plantarum and propionic acid improve the fermentation quality of high-moisture amaranth silage by altering the microbial community composition.  |  Zhao, M., et al. 2022. Front Microbiol. 13: 1066641. PMID: 36620031

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Propionic Acid, 25 ml

sc-470985
25 ml
$36.00

Propionic Acid, 500 ml

sc-470985A
500 ml
$40.00