Date published: 2025-9-27

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Propineb (CAS 12071-83-9)

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Alternate Names:
Zinc propylenebis(dithiocarbamate)
Application:
Propineb is pesticides and plant growth
CAS Number:
12071-83-9
Molecular Weight:
289.78
Molecular Formula:
C5H8N2S4Zn
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Propineb is a monopolymer propylene analog of zineb. It is classified as a pesticide that inhibits the spore germination on the sheet surface. Propineb, a member of the dithiocarbamates (DTCs) group of fungicides, finds extensive application in both agriculture and horticulture. Its cost-effective production sets it apart, offering a broad range of chemical and biological reactivity. Comprising a polymeric zinc complex combined with the propylene 1,2-bis(dithiocarbamate) anionic ligand, Propineb serves as a potent fungicide, effectively managing an array of fungal ailments. These include downy mildew, brown rot, black rot, red fire, leaf spot, and blight in various crops such as grapes, tomatoes, potatoes, berries, citrus, rice, and tea. Its significance extends to being an agrochemical with antifungal properties. Classified as a dithiocarbamate salt, it takes on the form of a macromolecule and a zinc coordination entity, centered around the propylene 1,2-bis(dithiocarbamate) composition.


Propineb (CAS 12071-83-9) References

  1. Facilitation of acetylcholine signaling by the dithiocarbamate fungicide propineb.  |  Marinovich, M., et al. 2002. Chem Res Toxicol. 15: 26-32. PMID: 11800594
  2. Inhalation toxicity of propineb. Part II: Results of mechanistic studies in rats.  |  Pauluhn, J., et al. 2003. Inhal Toxicol. 15: 435-60. PMID: 12682857
  3. Dithiocarbamate propineb induces acetylcholine release through cytoskeletal actin depolymerization in PC12 cells.  |  Viviani, B., et al. 2008. Toxicol Lett. 182: 63-8. PMID: 18822360
  4. Persistence and safety risk assessment of propineb in Indian tea.  |  Banerjee, H., et al. 2010. Environ Monit Assess. 170: 311-4. PMID: 19911290
  5. Determination of propineb and its metabolites propylenethiourea and propylenediamine in banana and soil using gas chromatography with flame photometric detection and LC-MS/MS analysis.  |  Song, S., et al. 2018. J Environ Sci Health B. 53: 153-160. PMID: 29227190
  6. Method development and validation for low-level propineb and propylenethiourea analysis in baby food, infant formula and related matrices using liquid chromatography-tandem mass spectrometry.  |  Vaclavik, L., et al. 2018. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 35: 2387-2399. PMID: 30427270
  7. [Determination of thiram, propineb and metiram in mushroom by gas chromatography-mass spectrometry].  |  Zhang, J., et al. 2020. Wei Sheng Yan Jiu. 49: 267-271. PMID: 32290944
  8. Analytical method validation, dissipation and safety evaluation of combination fungicides fenamidone + mancozeb and iprovalicarb + propineb in/on tomato.  |  Kumar, YB., et al. 2020. J Food Sci Technol. 57: 2061-2069. PMID: 32431332
  9. Review of the existing maximum residue levels for propineb according to Article 12 of Regulation (EC) No 396/2005.  |  , ., et al. 2020. EFSA J. 18: e06233. PMID: 32831950
  10. Multiple toxicity of propineb in developing zebrafish embryos: Neurotoxicity, vascular toxicity, and notochord defects in normal vertebrate development.  |  Park, H., et al. 2021. Comp Biochem Physiol C Toxicol Pharmacol. 243: 108993. PMID: 33529709
  11. Luminescent determination of propineb fungicide by using a carbon quantum dots-europium ions system.  |  Ruiz-Medina, A., et al. 2022. Talanta. 240: 123205. PMID: 35026641
  12. Determination of propineb in vegetable samples after a coprecipitation strategy for its separation-preconcentration prior to its indirect determination by FAAS.  |  Soylak, M., et al. 2022. Food Chem. 388: 133002. PMID: 35468462
  13. Behavior of trifloxystrobin and propineb as combination product in tomato (Solanum lycopersicum) and their risk assessment for human health.  |  Litoriya, NS., et al. 2023. Biomed Chromatogr. e5660. PMID: 37085954
  14. Propineb induced notochord deformity, craniofacial malformation, and osteoporosis in zebrafish through dysregulated reactive oxygen species generation.  |  Yuan, W., et al. 2023. Aquat Toxicol. 261: 106596. PMID: 37290275

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Propineb, 250 mg

sc-229002
250 mg
$35.00