Propidium iodide solution CAS: 25535-16-4
MW: 668.39
A membrane-impermeable fluorescent nucleic acid stain.

Propidium iodide solution (CAS 25535-16-4)

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Application: Propidium iodide solution is a membrane-impermeable fluorescent nucleic acid stain
CAS Number: 25535-16-4
Molecular Weight: 668.39
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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Propidium iodide is a laboratory reagent for the fluorescent staining of nucleic acids. Useful for flow cytometry for staining apoptotic cells and nuclei. Because it is membrane impermeable the state of the cell determines the ability of propidium iodide from staining viable and apoptotic cells. Propidium iodide has been used in in combination with Hoechst fluorescent stain (sc-202503) to observe cell viability via fluorescent microscopy. Propidium iodide is excitable at 536 nm and Emits at 617 nm (red).


References

1. Tas, J. and Westerneng, G. 1981. J. Histochem. Cytochem. 29(8): 929-936. PMID: 6168679

2. Darzynkiewicz, Z. et al. 1992. Cytometry. 13(8): 795-808. PMID: 1333943

3. Darzynkiewicz, Z. and Traganos, F. 1998. Adv. Biochem. Eng. Biotechnol. 62 : 33-73. PMID: 9755640

4. Darzynkiewicz, Z. and Bedner, E. 2000. Meth. Enzymol. 322 : 18-39. PMID: 10914002

Formulation :
10 mM aqueous solution
Physical State :
Liquid
Storage :
Desiccate at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
104981
SMILES :
CC[N+](C)(CC)CCC[N+]1=C2C=C(C=CC2=C3C=CC(=CC3=C1C4=CC=CC=C4)N)N.[I-].[I-]

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PMID: # 30078088  Purinergic Signal. 14: 395-408.

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