Molecular structure of Propargyl isothiocyanate, CAS Number: 24309-48-6
Propargyl isothiocyanate (CAS 24309-48-6)
Alternate Names:
3-isothiocyanatoprop-1-yne
CAS Number:
24309-48-6
Molecular Weight:
97.14
Molecular Formula:
C4H3NS
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Propargyl isothiocyanate is a versatile and potent chemical reagent widely used in organic synthesis and biochemistry. It is a colorless liquid, characterized by its robust scent, functions as an alkylating agent that is highly reactive. It can be used as a reagent for the synthesis of diverse compounds, including amino acids, peptides, and nucleic acids. As an alkylating agent it works by forming covalent bonds between the target compound′s molecules and the propargyl isothiocyanate. This reaction occurs when the nitrogen atom of propargyl isothiocyanate molecule is attacked by the electron-rich carbon atom of the target compound.
Propargyl isothiocyanate (CAS 24309-48-6) References
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- Cascade Reaction of Propargyl Amines with AgSCF3, as Well as One-Pot Reaction of Propargyl Amines, AgSCF3, and Di- tert-butyl Peroxide: Access to Allenyl Thiocyanates and Allenyl Trifluoromethylthioethers. | Zhen, L., et al. 2018. Org Lett. 20: 3109-3113. PMID: 29745677
- Effects of sulfide and polysulfides transmitted by direct or signal transduction-mediated activation of TRPA1 channels. | Pozsgai, G., et al. 2019. Br J Pharmacol. 176: 628-645. PMID: 30292176
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- Synthesis of Thiocarbamoyl Fluorides and Isothiocyanates Using CF3SiMe3 and Elemental Sulfur or AgSCF3 and KBr with Amines. | Zhen, L., et al. 2019. Org Lett. 21: 2106-2110. PMID: 30855147
- Programming Diffusion and Localization of DNA Signals in 3D-Printed DNA-Functionalized Hydrogels. | Müller, J., et al. 2020. Small. 16: e2001815. PMID: 32597010
- Discovery of simplified benzazole fragments derived from the marine benzosceptrin B as necroptosis inhibitors involving the receptor interacting protein Kinase-1. | Benchekroun, M., et al. 2020. Eur J Med Chem. 201: 112337. PMID: 32659605
- Bioactive Compounds and Signaling Pathways of Wolfiporia extensa in Suppressing Inflammatory Response by Network Pharmacology. | Jin, J., et al. 2023. Life (Basel). 13: PMID: 37109422
- 2-Acetylpyridine thiosemicarbazones. 2. N4,N4-Disubstituted derivatives as potential antimalarial agents. | Klaymann, DL., et al. 1979. J Med Chem. 22: 1367-73. PMID: 392099
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Propargyl isothiocyanate, 1 g | sc-286697 | 1 g | $103.00 | |||
Propargyl isothiocyanate, 5 g | sc-286697A | 5 g | $390.00 |