Molecular structure of Progesterone-d9, CAS Number: 15775-74-3
Progesterone-d9 (CAS 15775-74-3)
Alternate Names:
CIDR-d9; Corlutin-d9; Corlutina-d9; Corluvite-d9; Gestone-d9; Progestan-d9; Progestasert-d9; Progestogel-d9; Progesterone-2,2,4,6,6,17a,21,21,21-d9
Application:
Progesterone-d9 is steroid hormone produced by the corpus luteum
CAS Number:
15775-74-3
Molecular Weight:
323.52
Molecular Formula:
C21H21D9O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Progesterone-d9 is a deuterated analog of progesterone, a naturally occurring steroid that plays a role in the menstrual cycle and pregnancy. In research, progesterone-d9 is used as an internal standard for mass spectrometric analysis due to its stable isotopic labeling. It assists in the accurate quantification of progesterone levels in various biological samples by providing a reference point that corrects for sample preparation and analytical variations. This compound is also used in studies of steroid metabolism and hormone regulation, where the presence of deuterium atoms allows for the detailed tracking of metabolic transformations. Additionally, researchers utilize progesterone-d9 in the synthesis of other deuterated steroid analogs and for the development of sensitive and selective assays for hormone detection in environmental and biological systems.
Progesterone-d9 (CAS 15775-74-3) References
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- Steroid hormone regulation of angiogenesis in the primate endometrium. | Albrecht, ED. and Pepe, GJ. 2003. Front Biosci. 8: d416-29. PMID: 12456304
- Progesterone receptors--animal models and cell signalling in breast cancer. Diverse activation pathways for the progesterone receptor: possible implications for breast biology and cancer. | Lanari, C. and Molinolo, AA. 2002. Breast Cancer Res. 4: 240-3. PMID: 12473170
- MAP kinases couple multiple functions of human progesterone receptors: degradation, transcriptional synergy, and nuclear association. | Qiu, M. and Lange, CA. 2003. J Steroid Biochem Mol Biol. 85: 147-57. PMID: 12943699
- Development and Validation of LC-MS/MS Assay for the Quantification of Progesterone in Rat Plasma and its Application to Pharmacokinetic Studies. | Sasaki, M., et al. 2015. Drug Res (Stuttg). 65: 484-9. PMID: 25264857
- Determination of androgens and progestogens in environmental and biological samples using fabric phase sorptive extraction coupled to ultra-high performance liquid chromatography tandem mass spectrometry. | Guedes-Alonso, R., et al. 2016. J Chromatogr A. 1437: 116-126. PMID: 26858117
- Profiling adrenal 11β-hydroxyandrostenedione metabolites in prostate cancer cells, tissue and plasma: UPC2-MS/MS quantification of 11β-hydroxytestosterone, 11keto-testosterone and 11keto-dihydrotestosterone. | du Toit, T., et al. 2017. J Steroid Biochem Mol Biol. 166: 54-67. PMID: 27345701
- Application of microwave-assisted extraction and ultra-high performance liquid chromatography-tandem mass spectrometry for the analysis of sex hormones and corticosteroids in sewage sludge samples. | Guedes-Alonso, R., et al. 2016. Anal Bioanal Chem. 408: 6833-44. PMID: 27503545
- Influence of Acidification on the Partitioning of Steroid Hormones among Filtrate, Filter Media, and Retained Particulate Matter. | Havens, SM., et al. 2016. J Environ Qual. 45: 1776-1781. PMID: 27695756
- Sex-dependent changes in neuroactive steroid concentrations in the rat brain following acute swim stress. | Sze, Y., et al. 2018. J Neuroendocrinol. 30: e12644. PMID: 30194779
- Determination of hormones in human urine by ultra-high-performance liquid chromatography/triple-quadrupole mass spectrometry. | Zhou, Y. and Cai, Z. 2020. Rapid Commun Mass Spectrom. 34 Suppl 1: e8583. PMID: 31498943
- LC-MS/MS Method for Rapid Quantification of Progesterone in Rabbit Plasma and Its Application in a Pharmacokinetic Study of the Transdermal Formulation. | Tran, CS., et al. 2020. J Anal Methods Chem. 2020: 8889375. PMID: 33178479
- Pharmacokinetics, safety and bioequivalence of two formulations of progesterone soft capsule in healthy Chinese postmenopausal females: Impacts of a high-fat meal. | Qin, H., et al. 2022. Basic Clin Pharmacol Toxicol. 130: 268-276. PMID: 34806331
- Can analyte protectants compensate wastewater matrix induced enhancement effects in gas chromatography - mass spectrometry analysis? | Jørgensen, MB. and Christensen, JH. 2022. J Chromatogr A. 1676: 463280. PMID: 35785676
- Relationships between cause of death and concentrations of seven steroids obtained from the serum and cerebrospinal fluid of cadavers. | Nishio, T., et al. 2023. J Forensic Leg Med. 96: 102516. PMID: 37011448
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Progesterone-d9, 1 mg | sc-219647 | 1 mg | $360.00 |