Date published: 2026-4-30

1-800-457-3801

SCBT Portrait Logo
Seach Input

Procyanidin B2 (CAS 29106-49-8)

5.0(1)
Write a reviewAsk a question

See product citations (4)

Alternate Names:
4,8″-Bi-[(+)-epicatechin], cis; cis″-4,8″-Bi(3,3′,4′,5,7-pentahydroxyflavane)
CAS Number:
29106-49-8
Purity:
≥98%
Molecular Weight:
578.52
Molecular Formula:
C30H26O12
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

Procyanidin B2 is a proanthocyanidin consisting of two molecules of (−)-epicatechin joined by a bond between positions 4 and 8′ in a beta-configuration. It is a type of flavonoid compound that belongs to the class of condensed tannins. It is part of a larger group of compounds known as procyanidins, which are widely distributed in various plants, particularly in fruits, vegetables, and certain medicinal plants. It is known to scavenge free radicals and protect cells against oxidative damage.


Procyanidin B2 (CAS 29106-49-8) References

  1. Procyanidin B2 inhibits the activation of hepatic stellate cells and angiogenesis via the Hedgehog pathway during liver fibrosis.  |  Feng, J., et al. 2019. J Cell Mol Med. 23: 6479-6493. PMID: 31328391
  2. Procyanidin B2 Promotes Intestinal Injury Repair and Attenuates Colitis-Associated Tumorigenesis via Suppression of Oxidative Stress in Mice.  |  Zhu, X., et al. 2021. Antioxid Redox Signal. 35: 75-92. PMID: 32940048
  3. Procyanidin B2 induces porcine skeletal slow-twitch myofiber gene expression by AMP-activated protein kinase signaling pathway.  |  Xu, M., et al. 2022. Anim Biotechnol. 33: 346-355. PMID: 34061706
  4. Procyanidin B2 Reduces Vascular Calcification through Inactivation of ERK1/2-RUNX2 Pathway.  |  Liang, Y., et al. 2021. Antioxidants (Basel). 10: PMID: 34198832
  5. Procyanidin B2 ameliorates endothelial dysfunction and impaired angiogenesis via the Nrf2/PPARγ/sFlt-1 axis in preeclampsia.  |  Liu, L., et al. 2022. Pharmacol Res. 177: 106127. PMID: 35150862
  6. Procyanidin B2 inhibits angiogenesis and cell growth in oral squamous cell carcinoma cells through the vascular endothelial growth factor (VEGF)/VEGF receptor 2 (VEGFR2) pathway.  |  Sun, Q., et al. 2022. Bioengineered. 13: 6500-6508. PMID: 35220896
  7. Procyanidin B2 Protects Aged Oocytes Against Meiotic Defects Through Cortical Tension Modulation.  |  Zhuan, Q., et al. 2022. Front Vet Sci. 9: 795050. PMID: 35464357
  8. Procyanidin B2 Attenuates Nicotine-Induced Hepatocyte Pyroptosis through a PPARγ-Dependent Mechanism.  |  Liu, J., et al. 2022. Nutrients. 14: PMID: 35565726
  9. Mitochondrial PKM2 deacetylation by procyanidin B2-induced SIRT3 upregulation alleviates lung ischemia/reperfusion injury.  |  Zhao, J., et al. 2022. Cell Death Dis. 13: 594. PMID: 35821123
  10. Procyanidin B2 suppresses hyperglycemia-induced renal mesangial cell dysfunction by modulating CAV-1-dependent signaling.  |  Yin, J., et al. 2022. Exp Ther Med. 24: 496. PMID: 35837062
  11. Procyanidin B2 Alleviates Heat-Induced Oxidative Stress through the Nrf2 Pathway in Bovine Mammary Epithelial Cells.  |  Wang, H., et al. 2022. Int J Mol Sci. 23: PMID: 35887117
  12. Antioxidant procyanidin B2 protects oocytes against cryoinjuries via mitochondria regulated cortical tension.  |  Zhuan, Q., et al. 2022. J Anim Sci Biotechnol. 13: 95. PMID: 35971139
  13. Procyanidin B2 Protects TR-iBRB2 Cells Against Hyperglycemia Stress by Attenuating Oxidative Stress and Inflammasome Activation via Regulation of Redoxosomes/NF-kB Signaling.  |  Zou, W., et al. 2022. Curr Mol Med.. PMID: 36263472
  14. Procyanidin B2 ameliorates the progression of osteoarthritis: An in vitro and in vivo study.  |  Cai, W., et al. 2022. Int Immunopharmacol. 113: 109336. PMID: 36274486
  15. Procyanidin B2 alleviates oxidative stress-induced nucleus pulposus cells apoptosis through upregulating Nrf2 via PI3K-Akt pathway.  |  Zou, YP., et al. 2022. J Orthop Res.. PMID: 36448180

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Procyanidin B2, 500 µg

sc-236464A
500 µg
$82.00

Procyanidin B2, 1 mg

sc-236464
1 mg
$133.00

Procyanidin B2, 5 mg

sc-236464B
5 mg
$449.00