Probenecid-d14 MF: C13H5D14NO4S
MW: 299.45
A labeled inhibitor of Mdr-1 that prevents cellular efflux of active compounds.

Probenecid-d14

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Alternate Names: 4[(Dipropylamino-d14)sulfonyl]benzoic Acid
Application: Probenecid-d14 is a labeled inhibitor of MRP that prevents cellular efflux of active compounds
Molecular Weight: 299.45
Molecular Formula: C13H5D14NO4S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Probenecid-d14 is a labeled inhibitor of multidrug resistance-associated proteins (MRP), interferes with kidney organic ion transporters (OATs) to prevent reabsorption of uric acid. A VRL-1 iagonist and inhibitor of T2R16.


References

McKinney, S.E., et al.: J. Pharmacol. Exp. Ther., 102, 208 (1951) Israili, Z.H., et al.: J. Med. Chem., 15, 709 (1972) Al-Badr, A.A., et al.: Anal. Profiles Drug Subs., 10, 639 (1981) Cunningham, R.F., et al.: Clin. Pharmacokinet., 6, 135 (1981)

Physical State :
Solid
Solubility :
Soluble in Chloroform, Dichloromethane and Methanol
Storage :
Store at 4° C
Melting Point :
193-195° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
46782784
SMILES :
[2H]C([2H])([2H])C([2H])([2H])C([2H])([2H])N(C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])S(=O)(=O)C1=CC=C(C=C1)C(O)=O

Download SDS (MSDS)

Certificate of Analysis

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