Pristimerin (CAS 1258-84-0)
QUICK LINKS
Pristimerin is a naturally occurring quinonemethide triterpenoid that has garnered interest in various research disciplines. It is frequently studied in the context of biochemistry for its role in modulating enzyme activities and signaling pathways. In plant biology, Pristimerin is researched for its function as a phytoalexin, a substance that is part of the plant′s defense mechanism against pathogens. Chemists investigate the compound′s unique structure to understand its interaction with other molecules and to synthesize analogs with potentially modified properties. Additionally, Pristimerin is used in studies on cellular metabolism, where it is investigated for its potential effects on different metabolic pathways. The compound also serves as a reference molecule in analytical studies aimed at developing methods for its detection and quantification in complex biological matrices.
Pristimerin (CAS 1258-84-0) References
- Anti-Cancer Effects of Pristimerin and the Mechanisms: A Critical Review. | Li, JJ., et al. 2019. Front Pharmacol. 10: 746. PMID: 31354475
- Pristimerin suppresses colorectal cancer through inhibiting inflammatory responses and Wnt/β-catenin signaling. | Zhao, Q., et al. 2020. Toxicol Appl Pharmacol. 386: 114813. PMID: 31715269
- Attenuation of pristimerin on TNF-α-induced endothelial inflammation. | Liang, J., et al. 2020. Int Immunopharmacol. 82: 106326. PMID: 32135490
- Pristimerin-induced uveal melanoma cell death via inhibiting PI3K/Akt/FoxO3a signalling pathway. | Yan, F., et al. 2020. J Cell Mol Med. 24: 6208-6219. PMID: 32347651
- Pristimerin Suppressed Breast Cancer Progression via miR-542-5p/DUB3 Axis. | Cheng, S., et al. 2020. Onco Targets Ther. 13: 6651-6660. PMID: 32753899
- Pristimerin induces apoptosis and inhibits proliferation, migration in H1299 Lung Cancer Cells. | Li, J., et al. 2020. J Cancer. 11: 6348-6355. PMID: 33033518
- Pristimerin Suppresses Trophoblast Cell Epithelial-Mesenchymal Transition via miR-542-5p/EGFR Axis. | Shu, C., et al. 2020. Drug Des Devel Ther. 14: 4659-4670. PMID: 33173276
- Pristimerin synergizes with gemcitabine through abrogating Chk1/53BP1-mediated DNA repair in pancreatic cancer cells. | Jiang, Z., et al. 2021. Food Chem Toxicol. 147: 111919. PMID: 33301843
- Cellular and Molecular Mechanisms of Pristimerin in Cancer Therapy: Recent Advances. | Chen, RZ., et al. 2021. Front Oncol. 11: 671548. PMID: 34026649
- The multifaceted mechanisms of pristimerin in the treatment of tumors state-of-the-art. | Wang, Y., et al. 2022. Biomed Pharmacother. 154: 113575. PMID: 35988422
- Pristimerin, a triterpene that inhibits monoacylglycerol lipase activity, prevents the development of paclitaxel-induced allodynia in mice. | Al-Romaiyan, A. and Masocha, W. 2022. Front Pharmacol. 13: 944502. PMID: 36016571
- Lupeol and pristimerin do not inhibit activation of the human sperm CatSper Ca(2+)-channel. | Rehfeld, A. and Marcus Pedersen, C. 2022. F1000Res. 11: 222. PMID: 36016990
- Pristimerin mediated anticancer effects and sensitization of human skin cancer cells through modulation of MAPK signaling pathways. | Al-Tamimi, M., et al. 2022. Biomed Pharmacother. 156: 113950. PMID: 36411635
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Pristimerin, 5 mg | sc-281138 | 5 mg | $163.00 | |||
Pristimerin, 25 mg | sc-281138A | 25 mg | $490.00 |