Date published: 2026-2-10

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Primulin (CAS 8064-60-6)

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Alternate Names:
Direct Yellow 59
Application:
Primulin is a fluorescent dye containing the benzothiazole ring system
CAS Number:
8064-60-6
Molecular Weight:
475.54
Molecular Formula:
C21H14N3O3S3Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Primulin is a fluorescent dye that is widely employed in the field of cell biology and microscopy. It is particularly useful for staining acidic cell components, such as sulfated polysaccharides. In botanical research, Primulin is often used to stain and visualize plant cell walls, which allows for the detailed observation of cell morphology and structure. Additionally, its ability to bind to specific cellular materials without significant cytotoxicity makes it useful for live-cell imaging. Researchers also utilize Primulin in histochemical studies to differentiate tissues based on their chemical composition. The dye′s fluorescent properties enable the tracking and quantification of cellular and subcellular processes, making it a vital component in the arsenal of stains used for fluorescence microscopy. Moreover, it is studied for its interactions with various biological polymers, aiding in the understanding of cell wall biosynthesis and modification.


Primulin (CAS 8064-60-6) References

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  2. The reaction between phosphatidylethanolamines and HOCl investigated by TLC: fading of the dye primuline is induced by dichloramines.  |  Richter, G., et al. 2008. J Chromatogr B Analyt Technol Biomed Life Sci. 867: 233-7. PMID: 18440878
  3. Inhibition of rotavirus infectivity by a neoglycolipid receptor mimetic.  |  Bergner, DW., et al. 2011. Nutrients. 3: 228-44. PMID: 22254094
  4. Primuline derivatives that mimic RNA to stimulate hepatitis C virus NS3 helicase-catalyzed ATP hydrolysis.  |  Sweeney, NL., et al. 2013. J Biol Chem. 288: 19949-57. PMID: 23703611
  5. Benzothiazole and Pyrrolone Flavivirus Inhibitors Targeting the Viral Helicase.  |  Sweeney, NL., et al. 2015. ACS Infect Dis. 1: 140-148. PMID: 26029739
  6. Reliable Screening of Dye Phototoxicity by Using a Caenorhabditis elegans Fast Bioassay.  |  Bianchi, JI., et al. 2015. PLoS One. 10: e0128898. PMID: 26039060
  7. A study of the retinal ganglion cell which has an uncrossed bifurcating axon in the albino rat.  |  Yamadori, T., et al. 1989. Brain Res. 488: 143-8. PMID: 2743111
  8. Chemical composition of the yeast ascospore wall. The second outer layer consists of chitosan.  |  Briza, P., et al. 1988. J Biol Chem. 263: 11569-74. PMID: 3042773
  9. Characterization of E 472 food emulsifiers by high-performance thin-layer chromatography with fluorescence detection and mass spectrometry.  |  Oellig, C., et al. 2020. J Chromatogr A. 1618: 460874. PMID: 31959457
  10. The Inhibitory Effects and Cytotoxic Activities of the Stem Extract of Sarracenia purpurea against Melanoma Cells and the SsbA Protein.  |  Liu, HW., et al. 2022. Plants (Basel). 11: PMID: 36432892
  11. Large bodies of Mycoplasma and L-form organisms.  |  Kang, KS. and Casida, LE. 1967. J Bacteriol. 93: 1137-42. PMID: 6025418
  12. Selective uptake of lucifer yellow by retinal cells.  |  Sarthy, PV., et al. 1982. J Comp Neurol. 206: 371-8. PMID: 6284806
  13. [Initial neurons of the associative and callosal pathways of the lateral suprasylvian area of the cat brain].  |  Otellin, VA. and Meshkenaĭte, VI. 1984. Arkh Anat Gistol Embriol. 87: 14-21. PMID: 6508553
  14. Retrograde labeling and dissociation of mouse retinal ganglion cells.  |  Sarthy, PV. and Balkema, GW. 1981. Neurosci Lett. 25: 205-8. PMID: 7027093

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Primulin, 5 g

sc-296133
5 g
$104.00

Primulin, 25 g

sc-296133A
25 g
$307.00

Primulin, 100 g

sc-296133B
100 g
$780.00