Date published: 2026-4-25

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Prednisolone-d8 (Major) (CAS 50-24-8 (unlabeled))

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Alternate Names:
(11β)-11,17,21-Trihydroxy-pregna-1,4-diene-3,20-dione-d8; Metacortandralone-d8; Delta F-d8; Hydrocortisone-d8; Hydroretrocortine-d8
CAS Number:
50-24-8 (unlabeled)
Molecular Weight:
368.49
Molecular Formula:
C21H20D8O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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The introduction of deuterium atoms at specific positions in the molecule, replacing hydrogen, confers distinctive physical and chemical properties, such as increased metabolic stability and a reduced rate of degradation, which are particularly advantageous in metabolic studies. This isotopic labeling allows for precise tracking and quantification of prednisolone′s dynamics within biological systems, without altering its mechanism of action. Prednisolone-d8 (Major) is extensively utilized in mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy to elucidate the pharmacokinetics, distribution, metabolism, and excretion (ADME) profiles of glucocorticoids in research applications.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Prednisolone-d8 (Major), 1 mg

sc-477040
1 mg
$607.00