Molecular structure of Prednisolone-d6, CAS Number: 50-24-8 (unlabeled)
Prednisolone-d6 (CAS 50-24-8 (unlabeled))
Alternate Names:
Metacortandralone-d6
Application:
Prednisolone-d6 is a synthetic corticosteroid that is metabolically interconvertible with prednisone
CAS Number:
50-24-8 (unlabeled)
Purity:
95%
Molecular Weight:
366.48
Molecular Formula:
C21H20D6O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
Prednisolone-d6 is a stable isotope of prednisolone, a glucocorticoid with anti-inflammatory and immunosuppressive properties. Prednisolone-d6 functions as a tracer or internal standard for the quantification of prednisolone in biological samples using mass spectrometry. Its deuterium-labeled structure allows for precise and accurate measurement of prednisolone levels in various experimental conditions. Prednisolone-d6 interacts with the same molecular targets as prednisolone, binding to glucocorticoid receptors and modulating gene expression involved in inflammatory and immune responses.
Prednisolone-d6 (CAS 50-24-8 (unlabeled)) References
- Prednisolone measurement in human serum using liquid chromatography tandem mass spectrometry. | Owen, LJ., et al. 2005. Ann Clin Biochem. 42: 105-11. PMID: 15829118
- Demonstration of proof of mechanism and pharmacokinetics and pharmacodynamic relationship with 4'-cyano-biphenyl-4-sulfonic acid (6-amino-pyridin-2-yl)-amide (PF-915275), an inhibitor of 11 -hydroxysteroid dehydrogenase type 1, in cynomolgus monkeys. | Bhat, BG., et al. 2008. J Pharmacol Exp Ther. 324: 299-305. PMID: 17921190
- Development and validation of a liquid chromatography-tandem mass spectrometry method for the simultaneous determination of nine corticosteroid residues in bovine liver samples. | Dusi, G., et al. 2011. Anal Chim Acta. 700: 49-57. PMID: 21742116
- Quantification of 6 glucocorticoids in human plasma by liquid chromatography tandem mass spectrometry: method development, validation, and assessment of matrix effects. | Sæves, I., et al. 2011. Ther Drug Monit. 33: 402-10. PMID: 21743383
- Full-scan high resolution accurate mass spectrometry (HRMS) in regulated bioanalysis: LC-HRMS for the quantitation of prednisone and prednisolone in human plasma. | Fung, EN., et al. 2011. J Chromatogr B Analyt Technol Biomed Life Sci. 879: 2919-27. PMID: 21907643
- A liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for monitoring drug exposure in hematopoietic stem cell transplant recipients. | Laverdière, I., et al. 2012. J Chromatogr B Analyt Technol Biomed Life Sci. 885-886: 131-7. PMID: 22265668
- Multisteroid LC-MS/MS assay for glucocorticoids and androgens, and its application in Addison's disease. | Methlie, P., et al. 2013. Endocr Connect. 2: 125-136. PMID: 23825158
- The presence of prednisolone in complementary feedstuffs for bovine husbandry. | Chiesa, L., et al. 2014. J Sci Food Agric. 94: 2331-7. PMID: 24415459
- Pseudoendogenous origin of prednisolone in pigs from the food chain. | Arioli, F., et al. 2015. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 32: 833-40. PMID: 25768050
- Suitability of bovine bile compared to urine for detection of free, sulfate and glucuronate boldenone, androstadienedione, cortisol, cortisone, prednisolone, prednisone and dexamethasone by LC-MS/MS. | Chiesa, L., et al. 2015. Food Chem. 188: 473-80. PMID: 26041220
- Study on cortisol, cortisone and prednisolone presence in urine of Chianina cattle breed. | Chiesa, L., et al. 2017. J Anim Physiol Anim Nutr (Berl). 101: 893-903. PMID: 27080058
- Bovine teeth as a novel matrix for the control of the food chain: liquid chromatography-tandem mass spectrometry detection of treatments with prednisolone, dexamethasone, estradiol, nandrolone and seven β2-agonists. | Chiesa, LM., et al. 2017. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 34: 40-48. PMID: 27845609
- Prednisolone Replacement Therapy Mimics the Circadian Rhythm More Closely Than Other Glucocorticoids. | Williams, EL., et al. 2016. J Appl Lab Med. 1: 152-161. PMID: 33626793
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Prednisolone-d6, 1 mg | sc-219641 | 1 mg | $305.00 | |||
Prednisolone-d6, 5 mg | sc-219641A | 5 mg | $1097.00 | |||
Prednisolone-d6, 10 mg | sc-219641B | 10 mg | $1785.00 | |||
Prednisolone-d6, 25 mg | sc-219641C | 25 mg | $4259.00 | |||
Prednisolone-d6, 50 mg | sc-219641D | 50 mg | $6125.00 |