Date published: 2025-11-22

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Pravastatin Lactone-D3 (CAS 1217769-04-4)

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Alternate Names:
(2S)-2-(Methyl-d3)butanoic Acid (1S,3S,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3-hydroxy-7-methyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl Ester
Application:
Pravastatin Lactone-D3 is a labeled metabolite of Pravastatin
CAS Number:
1217769-04-4
Molecular Weight:
409.53
Molecular Formula:
C23H31D3O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Pravastatin Lactone-D3 is primarily utilized as an internal standard in analytical chemistry for quantifying the concentration of pravastatin in various samples through techniques such as mass spectrometry. This deuterated compound provides a methodological advantage due to its similar physicochemical properties to non-deuterated pravastatin while being distinguishable based on its mass difference. It is integral in ensuring the accuracy and precision of analytical methods in research studies that focus on the environmental fate of statins or their behavior in complex biological matrices. Additionally, its use in metabolic studies helps in understanding the biotransformation pathways of statins. The compound also aids in research that examines the stability and degradation of pravastatin under different conditions.


Pravastatin Lactone-D3 (CAS 1217769-04-4) References

  1. Determination of pravastatin and pravastatin lactone in rat plasma and urine using UHPLC-MS/MS and microextraction by packed sorbent.  |  Vlčková, H., et al. 2012. Talanta. 90: 22-9. PMID: 22340111
  2. Development of MEPS-UHPLC–MS/MS multistatin methods for clinical analysis  |  Vlčková, H., Svoboda, P., Novák, O., Solich, P., & Nováková, L. 2016. Bioanalysis. 8(4): 333-349.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Pravastatin Lactone-D3, 1 mg

sc-219636
1 mg
$614.00