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Pralidoxime chloride functions as a cholinesterase reactivator in experimental applications. Its mechanism of action involves the reactivation of acetylcholinesterase, an enzyme that is for the proper functioning of the nervous system. When certain organophosphate compounds inhibit acetylcholinesterase, pralidoxime chloride can bind to the inhibited enzyme and restore its activity, thereby reversing the toxic effects of the organophosphate compound. This reactivation occurs through a process known as nucleophilic substitution, where pralidoxime chloride displaces the organophosphate compound from the active site of the enzyme. By restoring the activity of acetylcholinesterase, pralidoxime chloride plays a functional role in experimental studies aimed at understanding the mechanisms of organophosphate toxicity and developing potential interventions. Its ability to reactivate acetylcholinesterase may be valuable for investigating the molecular and cellular effects of organophosphate compounds on the nervous system.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Pralidoxime Chloride, 1 g | sc-212578 | 1 g | $140.00 |