Molecular structure of PPT, CAS Number: 263717-53-9
PPT (CAS 263717-53-9)
See product citations (3)
Alternate Names:
1,3,5-Tris(4-hydroxyphenyl)-4-propyl-1H-pyrazole
Application:
PPT is a potent and specific ERα agonist
CAS Number:
263717-53-9
Molecular Weight:
386.44
Molecular Formula:
C24H22N2O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
PPT, also known as Propyl pyrazole triol, is a versatile organic compound widely employed in scientific research due to its diverse applications and its role as a synthetic catalyst for the synthesis of different compounds. PPT exists as a white crystalline solid, comprising three propylene glycol molecules and one pyrazole molecule. Its precise mechanism of action involves acting as a catalyst for the formation of various compounds. The prevailing belief is that PPT interacts with the active sites of enzymes and proteins, facilitating their catalytic function in generating new compounds.
PPT (CAS 263717-53-9) References
- Estrogen receptor alpha and beta specific agonists regulate expression of synaptic proteins in rat hippocampus. | Waters, EM., et al. 2009. Brain Res. 1290: 1-11. PMID: 19596275
- The effect of estrogen compounds on human embryoid bodies. | Kim, H., et al. 2013. Reprod Sci. 20: 661-9. PMID: 23184660
- Gene repressive mechanisms in the mouse brain involved in memory formation. | Yu, NK. and Kaang, BK. 2016. BMB Rep. 49: 199-200. PMID: 26949020
- Estrogen receptors orchestrate cell growth and differentiation to facilitate liver regeneration. | Kao, TL., et al. 2018. Theranostics. 8: 2672-2682. PMID: 29774067
- Estrogen relaxes gastric muscle cells via a nitric oxide- and cyclic guanosine monophosphate-dependent mechanism: A sex-associated differential effect. | Al-Shboul, OA., et al. 2018. Exp Ther Med. 16: 1685-1692. PMID: 30186388
- Effects of Estrogen and Estrogen Receptors on Transcriptomes of HepG2 Cells: A Preliminary Study Using RNA Sequencing. | Shen, M., et al. 2018. Int J Endocrinol. 2018: 5789127. PMID: 30510575
- Nup133 and ERα mediate the differential effects of hyperoxia-induced damage in male and female OPCs. | Sunny, DE., et al. 2020. Mol Cell Pediatr. 7: 10. PMID: 32844334
- Bone tissue morphology of rat offspring lactationally exposed to polychlorinated biphenyl 169 and 155. | Brankovič, J., et al. 2020. Sci Rep. 10: 19016. PMID: 33149271
- A Multi-Omics Study Revealing the Metabolic Effects of Estrogen in Liver Cancer Cells HepG2. | Shen, M., et al. 2021. Cells. 10: PMID: 33672651
- Estrogen-Induced Uterine Vasodilation in Pregnancy and Preeclampsia. | Li, Y., et al. 2022. Matern Fetal Med. 4: 52-60. PMID: 35072088
- Therapeutic Value of Estrogen Receptor α in Hepatocellular Carcinoma Based on Molecular Mechanisms. | Meng, X. and Liu, X. 2022. J Clin Transl Hepatol. 10: 140-146. PMID: 35233383
- A Novel Estrogen Receptor β Agonist Diminishes Ovarian Cancer Stem Cells via Suppressing the Epithelial-to-Mesenchymal Transition. | Banerjee, A., et al. 2022. Cancers (Basel). 14: PMID: 35565440
- Discovery of Highly Functionalized 5-hydroxy-2H-pyrrol-2-ones That Exhibit Antiestrogenic Effects in Breast and Endometrial Cancer Cells and Potentiate the Antitumoral Effect of Tamoxifen. | Guerra-Rodríguez, M., et al. 2022. Cancers (Basel). 14: PMID: 36358593
- Lipedema: Insights into Morphology, Pathophysiology, and Challenges. | Poojari, A., et al. 2022. Biomedicines. 10: PMID: 36551837
Activator of:
ER alpha, and ERRα.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PPT, 10 mg | sc-297946 | 10 mg | $170.00 |