Molecular structure of PPHP, CAS Number: 87864-20-8
PPHP (CAS 87864-20-8)
Alternate Names:
5-phenyl-4E-pentenyl-1-hydroperoxide
Application:
PPHP is a peroxide used to assay peroxidase activity
CAS Number:
87864-20-8
Purity:
>98%
Molecular Weight:
178.2
Molecular Formula:
C11H14O2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
PPHP, 5-phenyl-4-pentenyl-1-hydroperoxide, is a small molecule peroxide employed as a substrate probe for peroxidase enzymes. Conversion of PPHP to 5-phenyl-4-pentenyl alcohol by peroxidase enzymes can be traced with HPLC to assay peroxidase activity. This approach has been exploited to assay the activity of COX-1 and COX-2, and can be used to identify and characterize other peroxide-reducing enzymes.
PPHP (CAS 87864-20-8) References
- Detection of a higher oxidation state of manganese-prostaglandin endoperoxide synthase. | Odenwaller, R., et al. 1992. J Biol Chem. 267: 13863-9. PMID: 1321128
- Peroxidase active site activity assay. | Duggan, KC., et al. 2010. Methods Mol Biol. 644: 55-65. PMID: 20645165
- Competition and allostery govern substrate selectivity of cyclooxygenase-2. | Mitchener, MM., et al. 2015. Proc Natl Acad Sci U S A. 112: 12366-71. PMID: 26392530
- Enzymatic reduction of 5-phenyl-4-pentenyl-hydroperoxide: detection of peroxidases and identification of peroxidase reducing substrates. | Weller, PE., et al. 1985. Arch Biochem Biophys. 243: 633-43. PMID: 4083906
Substrate of:
HRP and AP.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PPHP, 500 µg | sc-204856 | 500 µg | $156.00 | |||
PPHP, 1 mg | sc-204856A | 1 mg | $296.00 |