PPARγ Antagonist III, G3335 (CAS 36099-95-3)
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PPARγ Antagonist III, G3335 is a cell-permeable dipeptide that acts as a selective and reversible PPAR gamma antagonist (KD ~ 8 muM). Shown to inhibit the agonist activity of Rosiglitazone (100 nM) in a dose-dependent manner (IC50 = 31.9 µM) in transfected COS-7 cells. PPARγ Antagonist III, G3335 is a small molecule compound that selectively inhibits the activity of peroxisome proliferator-activated receptor gamma (PPARγ), a nuclear receptor involved in regulating gene expression and various metabolic processes. By antagonizing PPARγ, this compound can modulate PPARγ-mediated transcriptional activity and downstream signaling pathways. It can be used to investigate the impact of inhibiting PPARγ activity on adipogenesis, and lipid metabolism.
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PPARγ Antagonist III, G3335, 50 mg | sc-202771 | 50 mg | $102.00 | |||
PPARγ Antagonist III, G3335, 100 mg | sc-202771A | 100 mg | $204.00 |