PP5 Antibody (G-6): sc-515257

PP5 Antibody (G-6) is a mouse monoclonal IgG1 antibody that detects PP5 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). PP5, also known as Protein phosphatase T, plays a crucial role in cellular regulation by dephosphorylating serine residues on various substrates, including skeletal muscle phosphorylase and histone H1, which are vital for processes such as mitosis and RNA biogenesis. Anti-PP5 antibody (G-6) targets a protein predominantly located in the nucleus, where PP5 is involved in the regulation of gene expression and cell cycle progression, making PP5 essential for maintaining cellular homeostasis and proper cell division. The trimeric structure of the PP5 holoenzyme, composed of a regulatory subunit, a variable subunit, and a catalytic subunit, allows for precise control over phosphatase activity, highlighting PP5′s importance in cellular signaling pathways. PP5 (G-6) antibody is an invaluable tool for researchers studying the intricate mechanisms of protein phosphorylation and its implications in various biological processes and diseases.

The preferred PP5 antibody is PP5 Antibody (H-7): sc-271816.