PP5 Antibody (F-8): sc-271613

PP5 Antibody (F-8) is a mouse monoclonal IgG2b antibody that detects PP5 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). PP5, also known as protein phosphatase T, plays a crucial role in cellular regulation by dephosphorylating serine residues on target proteins, which is vital for processes such as cell division, apoptosis, and maintaining cellular homeostasis. PP5 is predominantly located in the nucleus, where PP5 is involved in the regulation of mitosis and RNA biogenesis, highlighting its importance in cell cycle control and gene expression. The PP5 holoenzyme is a trimeric complex that includes a regulatory subunit, a variable subunit, and a catalytic subunit, allowing for precise modulation of its activity in response to cellular signals. Additionally, PP5 interacts with key proteins such as CDC16 and CDC27, which are essential for the proper progression of the cell cycle, further underscoring the significance of PP5 in maintaining cellular integrity and function. With broad reactivity and versatile applications, anti-PP5 antibody (F-8) is an invaluable tool for researchers studying the intricate mechanisms of protein phosphorylation and its implications in various biological processes.

The preferred PP5 antibody is PP5 Antibody (H-7): sc-271816.