PP2Cζ Antibody (D-4): sc-390213

PP2Cζ Antibody (D-4) is a mouse monoclonal IgG1 antibody that detects PP2Cζ in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). PP2Cζ, also known as PPM1J, is a crucial serine/threonine protein phosphatase that plays a significant role in cellular signaling pathways by regulating the phosphorylation state of various substrates. This regulation is vital for maintaining cellular functions such as division, homeostasis, and apoptosis. PP2Cζ consists of 505 amino acids and features a PP2C-like domain, which is essential for phosphatase activity. Notably, PP2Cζ is involved in the cellular response to stress and is recruited to specific substrates through interactions with small ubiquitin-related modifier-1 and UBC9, highlighting PP2Cζ′s importance in the ubiquitin-proteasome pathway. PP2Cζ′s ability to modulate these pathways underscores PP2Cζ′s potential as a therapeutic target in diseases where dysregulation of phosphorylation is implicated. With robust reactivity and versatility in various applications, anti-PP2Cζ antibody (D-4) serves as an invaluable tool for researchers studying the intricate mechanisms of cellular regulation and signaling.

The preferred PP2Cζ antibody is PP2Cζ Antibody (C-4): sc-390214.