PP1γ Antibody (AP-03): sc-517354

PP1γ Antibody (AP-03) is a mouse monoclonal IgG2b antibody engineered to recognize PP1γ protein, also known as PPP1CC or Protein Phosphatase 1 Gamma, an essential catalytic subunit of the Protein Phosphatase 1 (PP1) family. PP1γ is predominantly localized in both the nucleus and cytoplasm of eukaryotic cells, where PP1γ plays an essential role in regulating a myriad of cellular processes by dephosphorylating serine and threonine residues on target proteins. This dual localization is vital for controlling cell cycle progression, transcriptional regulation, and apoptosis, thereby maintaining cellular homeostasis and enabling dynamic responses to various cellular signals. The ability of PP1γ to modulate phosphorylation states is crucial for preventing aberrant cell growth and ensuring proper cellular function. Dysregulation of PP1γ has been implicated in numerous diseases, including cancer and neurodegenerative disorders, highlighting PP1γ′s significance as a potential therapeutic target. Anti-PP1γ antibody (AP-03) is raised against a recombinant human PP1γ protein and is recommended for the detection of human PP1γ by western blotting (WB) and immunoprecipitation (IP). The high specificity of PP1γ monoclonal antibody (AP-03) is an indispensable tool for researchers studying the intricate mechanisms of protein phosphorylation and dephosphorylation, as well as the broader regulatory networks that govern cellular function and disease pathology. By facilitating accurate detection and analysis of PP1γ, PP1γ (AP-03) antibody supports advancements in understanding the critical roles of protein phosphatases in health and disease, ultimately contributing to the development of targeted therapeutic strategies.

The preferred PP1γ antibody is PP1γ Antibody (E-4): sc-515943.