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Potassium methanesulfonate (CAS 2386-56-3)

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Alternate Names:
Methanesulfonic acid potassium salt; potassium mesylate
CAS Number:
2386-56-3
Purity:
99%
Molecular Weight:
134.20
Molecular Formula:
CH3KO3S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Potassium methanesulfonate is a sulfonic acid compound with antimicrobial properties. By disrupting the bacterial cell membrane it leads to a leakage of ions and water. characteristic makes it an effective preservative in cosmetics. Moreover, potassium methanesulfonate shows antibacterial efficacy against challenging strains like methicillin-resistant Staphylococcus aureus (MRSA) and Enterococcus faecium. It serves as a valuable cocatalyst in the ruthenium-catalyzed C-H arylation of heteroarylbenzenes.


Potassium methanesulfonate (CAS 2386-56-3) References

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  2. Coupling of c-Src to large conductance voltage- and Ca2+-activated K+ channels as a new mechanism of agonist-induced vasoconstriction.  |  Alioua, A., et al. 2002. Proc Natl Acad Sci U S A. 99: 14560-5. PMID: 12391293
  3. Ethanol enhances both action potential-dependent and action potential-independent GABAergic transmission onto cerebellar Purkinje cells.  |  Hirono, M., et al. 2009. Neuropharmacology. 57: 109-20. PMID: 19426745
  4. Selective T-type calcium channel block in thalamic neurons reveals channel redundancy and physiological impact of I(T)window.  |  Dreyfus, FM., et al. 2010. J Neurosci. 30: 99-109. PMID: 20053892
  5. New automated synthesis of [18F]FP-CIT with base amount control affording high and stable radiochemical yield: a 1.5-year production report.  |  Lee, SJ., et al. 2011. Nucl Med Biol. 38: 593-7. PMID: 21531297
  6. Ablation of smooth muscle caldesmon affects the relaxation kinetics of arterial muscle.  |  Guo, H., et al. 2013. Pflugers Arch. 465: 283-94. PMID: 23149489
  7. Dynamic regulation of glycine-GABA co-transmission at spinal inhibitory synapses by neuronal glutamate transporter.  |  Ishibashi, H., et al. 2013. J Physiol. 591: 3821-32. PMID: 23690564
  8. Receptor-coupled, permeabilized smooth muscle. Role of the phosphatidylinositol cascade, G-proteins, and modulation of the contractile response to Ca2+.  |  Kitazawa, T., et al. 1989. J Biol Chem. 264: 5339-42. PMID: 2494163
  9. Cytosolic heparin inhibits muscarinic and alpha-adrenergic Ca2+ release in smooth muscle. Physiological role of inositol 1,4,5-trisphosphate in pharmacomechanical coupling.  |  Kobayashi, S., et al. 1989. J Biol Chem. 264: 17997-8004. PMID: 2509451
  10. Structure and vibrational spectroscopy of lithium and potassium methanesulfonates.  |  Parker, SF., et al. 2020. R Soc Open Sci. 7: 200776. PMID: 32874662
  11. A Novel Method to Monitor GABA Loading into Synaptic Vesicles by Combining Patch Pipette Perfusion and Intracellular, Caged-GABA Photolysis in Brain Slice Preparations.  |  Yamashita, M. and Hori, T. 2022. Methods Mol Biol. 2417: 113-120. PMID: 35099795
  12. Introduction of high molecular weight (IgG) proteins into receptor coupled, permeabilized smooth muscle.  |  Iizuka, K., et al. 1994. Cell Calcium. 16: 431-45. PMID: 7712537
  13. Whole-cell recording of the Ca(2+)-dependent slow afterhyperpolarization in hippocampal neurones: effects of internally applied anions.  |  Zhang, L., et al. 1994. Pflugers Arch. 426: 247-53. PMID: 8183635
  14. Role of the S4 segment in a voltage-dependent calcium-sensitive potassium (hSlo) channel.  |  Díaz, L., et al. 1998. J Biol Chem. 273: 32430-6. PMID: 9829973

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Potassium methanesulfonate, 5 g

sc-236446
5 g
$48.00

Potassium methanesulfonate, 25 g

sc-236446A
25 g
$80.00

Potassium methanesulfonate, 100 g

sc-236446B
100 g
$222.00

Potassium methanesulfonate, 500 g

sc-236446C
500 g
$895.00