Molecular structure of Ponasterone A, CAS Number: 13408-56-5
Ponasterone A (CAS 13408-56-5)
See product citations (14)
Alternate Names:
Ponasterone A is also known as 25-Deoxyecdysterone.
Application:
Ponasterone A is an insect steroid hormone analog that can regulate the metamorphosis of Drosphila.
CAS Number:
13408-56-5
Purity:
>95%
Molecular Weight:
464.64
Molecular Formula:
C27H44O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Ponasterone A is an insect hormone involved in regulating metamorphosis. Ponasterone A is an analog of ecdysone A and a member of the ecdysteroid family with similar properties to muristerone A. Ponasterone A is a functional, reliable and economical substitute for muristerone A as an inducer for the ecdysone-inducible mammalian expression system. Additionally, Ponasterone A is an analog of 20-hydroxy ecdysone.
Ponasterone A (CAS 13408-56-5) References
- Sustained mammary gland-directed, ponasterone A-inducible expression in transgenic mice. | Albanese, C., et al. 2000. FASEB J. 14: 877-84. PMID: 10783141
- Identification of ligands and coligands for the ecdysone-regulated gene switch. | Saez, E., et al. 2000. Proc Natl Acad Sci U S A. 97: 14512-7. PMID: 11114195
- The ecdysone inducible gene expression system: unexpected effects of muristerone A and ponasterone A on cytokine signaling in mammalian cells. | Constantino, S., et al. 2001. Eur Cytokine Netw. 12: 365-7. PMID: 11399528
- Recent advances in inducible expression in transgenic mice. | Albanese, C., et al. 2002. Semin Cell Dev Biol. 13: 129-41. PMID: 12240598
- Development of a ponasterone A-inducible gene expression system for application in cultured skeletal muscle cells. | Xiao, YY., et al. 2003. Int J Biochem Cell Biol. 35: 79-85. PMID: 12467649
- Past and present studies with ponasterones, the first insect molting hormones from plants. | Nakanishi, K. 1992. Steroids. 57: 649-57. PMID: 1481229
- Synthesis of ponasterone A derivatives with various steroid skeleton moieties and evaluation of their binding to the ecdysone receptor of Kc cells. | Arai, H., et al. 2008. Steroids. 73: 1452-64. PMID: 18804484
- Establishment of ponasterone A-inducible the wild-type p53 protein-expressing clones from HSC-1 cells, cell growth suppression by p53 expression and the suppression mechanism. | Hori, M., et al. 2009. Arch Dermatol Res. 301: 631-46. PMID: 19009304
- Genome-wide examination of the transcriptional response to ecdysteroids 20-hydroxyecdysone and ponasterone A in Drosophila melanogaster. | Gonsalves, SE., et al. 2011. BMC Genomics. 12: 475. PMID: 21958154
- Ponasterone A and F, Ecdysteroids from the Arctic Bryozoan Alcyonidium gelatinosum. | Hansen, KØ., et al. 2018. Molecules. 23: PMID: 29921766
- Overexpression of SMN2 Gene in Motoneuron-Like Cells Differentiated from Adipose-Derived Mesenchymal Stem Cells by Ponasterone A. | Mohseni, R., et al. 2019. J Mol Neurosci. 67: 247-257. PMID: 30535775
- Pharmacological studies of insect metamorphosing hormone: ponasterone A, ecdysterone, and inokosterone, in the rat. | Masuoka, M., et al. 1970. Jpn J Pharmacol. 20: 142-56. PMID: 5311320
- The uptake and release of ponasterone A by the Kc cell line of Drosophila melanogaster. | Beckers, C., et al. 1980. Mol Cell Endocrinol. 17: 51-9. PMID: 6244205
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ponasterone A, 1 mg | sc-202768 | 1 mg | $77.00 | |||
Ponasterone A, 5 mg | sc-202768A | 5 mg | $277.00 | |||
Ponasterone A, 25 mg | sc-202768B | 25 mg | $1100.00 |