Polysorbate 60 (CAS 9005-67-8)
Alternate Names:
Tween 60
CAS Number:
9005-67-8
Molecular Weight:
1311.70
Molecular Formula:
C64H126O26
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
Polysorbate 60, classified as a hydrophilic nonionic surfactant, serves as a versatile emulsifier, dispersing agent, and solubilizer. It is a niosome. It belongs to the fatty acid esters category of organic compounds. Notably, Polysorbate 60 is predominantly found in the membrane and cytoplasm within the cell. It is characterized by being practically insoluble in water and relatively neutral in its molecular properties.
Polysorbate 60 (CAS 9005-67-8) References
- Stimulation of triglyceride-rich lipoprotein secretion by polysorbate 80: in vitro and in vivo correlation using Caco-2 cells and a cannulated rat intestinal lymphatic model. | Seeballuck, F., et al. 2004. Pharm Res. 21: 2320-6. PMID: 15648264
- Intestinal lymphatic transport of halofantrine in rats assessed using a chylomicron flow blocking approach: the influence of polysorbate 60 and 80. | Lind, ML., et al. 2008. Eur J Pharm Sci. 35: 211-8. PMID: 18675904
- Retinal gene delivery enhancement by lycopene incorporation into cationic niosomes based on DOTMA and polysorbate 60. | Mashal, M., et al. 2017. J Control Release. 254: 55-64. PMID: 28347807
- Influence of Polysorbate 60 on Formulation Properties and Bioavailability of Morin-Loaded Nanoemulsions with and without Low-Saponification-Degree Polyvinyl Alcohol. | Ikeuchi-Takahashi, Y., et al. 2018. Biol Pharm Bull. 41: 754-760. PMID: 29709912
- A case of severe immediate type reaction to macrogol and polysorbate 60 after intravaginal drug application. | Schwede, K., et al. 2019. Eur J Dermatol. 29: 329-331. PMID: 31389792
- Challenges in polysorbate characterization by mass spectrometry. | Penfield, KW. and Rumbelow, S. 2020. Rapid Commun Mass Spectrom. 34 Suppl 2: e8709. PMID: 31943438
- Stabilization of vitamin C in emulsions of liquid crystalline structures. | Caritá, AC., et al. 2021. Int J Pharm. 592: 120092. PMID: 33212173
- Effect of Pharmaceutical Excipients on Intestinal Absorption of Metformin via Organic Cation-Selective Transporters. | Ruan, Y., et al. 2021. Mol Pharm. 18: 2198-2207. PMID: 33956455
- A comparison of emulsifiers for the formation of oil-in-water emulsions: stability of the emulsions within 9 h after production and MR signal properties. | Fritz, V., et al. 2022. MAGMA. 35: 401-410. PMID: 34698962
- Investigating the influence of excipient batch variation on the structure, consistency and physical stability of polysorbate 60-based topical vehicles. | Vu Dang, H., et al. 2021. Int J Cosmet Sci. 43: 715-728. PMID: 34714546
- Exogenous fatty acids affect membrane properties and cold adaptation of Listeria monocytogenes. | Flegler, A., et al. 2022. Sci Rep. 12: 1499. PMID: 35087150
- Optimization of Emulsification Conditions on Ethanol Extract of Taiwanese Green Propolis Using Polysorbate and Its Immunomodulatory Effects in Broilers. | Hsiao, FS., et al. 2022. Animals (Basel). 12: PMID: 35203153
- Formulation and Characterization of Epalrestat-Loaded Polysorbate 60 Cationic Niosomes for Ocular Delivery. | Kattar, A., et al. 2023. Pharmaceutics. 15: PMID: 37111732
- Influence of surface-active food additives on the integrity and permeability of rat intestinal mucosa. | Tagesson, C. and Edling, C. 1984. Food Chem Toxicol. 22: 861-4. PMID: 6094320
- The composition of NF-defined emulsifiers: sorbitan monolaurate, monopalmitate, monostearate, monooleate, polysorbate 20, polysorbate 40, polysorbate 60, and polysorbate 80. | Brandner, JD. 1998. Drug Dev Ind Pharm. 24: 1049-54. PMID: 9876559
Activator of:
CLEC-4E, and LYSMD2.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Polysorbate 60, 100 ml | sc-281134 | 100 ml | $37.00 | |||
Polysorbate 60, 500 ml | sc-281134A | 500 ml | $59.00 |