Polymixin E complex (CAS 1066-17-7 (for Polymyxin E1))
See product citations (3)
Alternate Names:
Colistin, Colimycin M, Belcomycin, Colymycin, Torazin
Application:
Polymixin E complex is A highly basic atypical cyclic peptide with antibiotic activity.
CAS Number:
1066-17-7 (for Polymyxin E1)
Molecular Weight:
1169.50 (for Polymyxin E1)
Molecular Formula:
C53H100N16O13 (for Polymyxin E1)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Polymyxin E complex is a complex of closely related cyclic peptides E1 and E2, with additional minor analogues. Polymyxin E is produced by Bacillus polymyxa var. colistinus and is a highly basic, atypical cyclic peptide which incorporates the unusual amino acid, diaminobutyric acid. Head-to-tail coupling of lysine completes the macrocycle. Balancing the polar cyclic peptide is a hydrophobic tail with short chain fatty acids. Polymyxin E is a broad spectrum antibiotic active against Gram negative bacteria. The mechanism of action involves disruption of the bacterial outer membrane by a detergent-like effect.
Polymixin E complex (CAS 1066-17-7 (for Polymyxin E1)) References
- Identification of impurities in polymyxin B and colistin bulk sample using liquid chromatography coupled to mass spectrometry. | Van den Bossche, L., et al. 2011. Talanta. 83: 1521-9. PMID: 21238747
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Polymixin E complex, 25 mg | sc-362784 | 25 mg | $96.00 | |||
Polymixin E complex, 5.5 g | sc-362784A | 5.5 g | $16320.00 |