Date published: 2026-4-24

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Polyglycolide (CAS 26124-68-5)

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Datasheets
Alternate Names:
PGA
CAS Number:
26124-68-5
Molecular Formula:
(C2H4O3)n
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Polyglycolide, known as poly(glycolic acid) or PGA, is a biodegradable polymer with a strong presence in the field of materials science for its role in creating bioresorbable devices. Its high tensile strength and ability to degrade hydrolytically make it a focus of research on the body′s interaction with bioresorbable implants and the safe absorption of degradation by-products. Additionally, polyglycolide′s controlled degradation rate is utilized in chemical delivery systems to achieve precise release timings. Beyond these applications, its potential contribution to developing sustainable packaging solutions positions it as an environmentally friendly alternative to conventional plastics, and its utility is further expanded through the synthesis of copolymers that adapt its properties for a range of specific uses.


Polyglycolide (CAS 26124-68-5) References

  1. Tissue response to polyglycolide and polylevolactide pins in osteotomized cancellous bone.  |  Nordström, P., et al. 2001. Clin Orthop Relat Res. 247-57. PMID: 11153995
  2. Controlled-release vaccines--biodegradable polylactide/polyglycolide (PL/PG) microspheres as antigen vehicles.  |  Aguado, MT. and Lambert, PH. 1992. Immunobiology. 184: 113-25. PMID: 1587538
  3. Polylactide-polyglycolide antibiotic implants.  |  Garvin, K. and Feschuk, C. 2005. Clin Orthop Relat Res. 105-10. PMID: 16056034
  4. Triclosan release from coated polyglycolide threads.  |  Zurita, R., et al. 2006. Macromol Biosci. 6: 58-69. PMID: 16374771
  5. Polylactide-polyglycolide resorbable plates stimulates adipose tissue-derived stem cells towards osteoblasts differentiation.  |  Sollazzo, V., et al. 2011. Int J Immunopathol Pharmacol. 24: 59-64. PMID: 21781447
  6. Biocompatibility and Bioresorption of 3D-Printed Polylactide and Polyglycolide Tissue Membranes.  |  Kim, EV., et al. 2021. Bull Exp Biol Med. 170: 356-359. PMID: 33452990
  7. Synthesis, Microstructure, and Properties of High-Molar-Mass Polyglycolide Copolymers with Isolated Methyl Defects.  |  Altay, E., et al. 2021. Biomacromolecules. 22: 2532-2543. PMID: 33970613
  8. Structural Evolution of Polyglycolide and Poly(glycolide-co-lactide) Fibers during the Heat-Setting Process.  |  Dong, Z., et al. 2021. Biomacromolecules. 22: 3342-3356. PMID: 34212713
  9. Structural Evolution of Polyglycolide and Poly(glycolide-co-lactide) Fibers during In Vitro Degradation with Different Heat-Setting Temperatures.  |  Miao, Y., et al. 2021. ACS Omega. 6: 29254-29266. PMID: 34746613
  10. Estimating the Relative Crystallinity of Biodegradable Polylactic Acid and Polyglycolide Polymer Composites by Machine Learning Methodologies.  |  Wang, J., et al. 2022. Polymers (Basel). 14: PMID: 35160516
  11. Design and production of single-immunization vaccines using polylactide polyglycolide microsphere systems.  |  Cleland, JL. 1995. Pharm Biotechnol. 6: 439-62. PMID: 7551230
  12. Absorbable polyglycolide devices in trauma and bone surgery.  |  Ashammakhi, N. and Rokkanen, P. 1997. Biomaterials. 18: 3-9. PMID: 9003889
  13. Polyglycolide bioabsorbable screws in the treatment of ankle fractures.  |  Hovis, WD. and Bucholz, RW. 1997. Foot Ankle Int. 18: 128-31. PMID: 9116891

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Polyglycolide, 5 g

sc-506517
5 g
$559.00