Date published: 2025-10-2

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Polydextrose (CAS 68424-04-4)

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Application:
Polydextrose is a water-soluble polymer composed of glucose subunits
CAS Number:
68424-04-4
Molecular Weight:
342.30
Molecular Formula:
C12H22O11
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Polydextrose is a distinctive form of dietary fiber with a multitude of applications in the food industry. This synthetic polymer of glucose and sorbitol serves as a low-calorie bulking agent, humectant, stabilizer, and texturizer. It′s been used as a substitute for sugar, fat, and other calorie-laden ingredients in the food sector for several years. It′s also been utilized in various industries for its capacity to enhance the solubility and bioavailability of certain compounds. Further, polydextrose has been researched for potential health advantages, including prebiotic effects, better glycemic regulation, and increased satiety. It undergoes slow fermentation in the large intestine by resident bacteria. This fermentation process yields short-chain fatty acids, beneficial for gut health. Furthermore, polydextrose is believed to function as a prebiotic, bolstering the growth of gut-friendly bacteria. It also heightens the viscosity of intestinal contents, which can decelerate glucose absorption and enhance glycemic regulation.


Polydextrose (CAS 68424-04-4) References

  1. A review of the studies of the safety of polydextrose in food.  |  Burdock, GA. and Flamm, WG. 1999. Food Chem Toxicol. 37: 233-64. PMID: 10227745
  2. Ingestion of polydextrose increase the iron absorption in rats submitted to partial gastrectomy.  |  Santos, EF., et al. 2010. Acta Cir Bras. 25: 518-24. PMID: 21120284
  3. Dietary fiber type reflects physiological functionality: comparison of grain fiber, inulin, and polydextrose.  |  Raninen, K., et al. 2011. Nutr Rev. 69: 9-21. PMID: 21198631
  4. Effects of feeding polydextrose on faecal characteristics, microbiota and fermentative end products in healthy adult dogs.  |  Beloshapka, AN., et al. 2012. Br J Nutr. 108: 638-44. PMID: 22085650
  5. The fermentation of polydextrose in the large intestine and its beneficial effects.  |  Röytiö, H. and Ouwehand, AC. 2014. Benef Microbes. 5: 305-13. PMID: 24736314
  6. Rapid microwave-assisted synthesis of polydextrose and identification of structure and function.  |  Wang, H., et al. 2014. Carbohydr Polym. 113: 225-30. PMID: 25256479
  7. Effects of polydextrose on different levels of energy intake. A systematic review and meta-analysis.  |  Ibarra, A., et al. 2015. Appetite. 87: 30-7. PMID: 25510531
  8. Prebiotics in infant formula.  |  Vandenplas, Y., et al. 2014. Gut Microbes. 5: 681-7. PMID: 25535999
  9. High-Fat Diet, Betaine, and Polydextrose Induce Changes in Adipose Tissue Inflammation and Metabolism in C57BL/6J Mice.  |  Airaksinen, K., et al. 2018. Mol Nutr Food Res. 62: e1800455. PMID: 30290084
  10. Polydextrose with and without Bifidobacterium animalis ssp. lactis 420 drives the prevalence of Akkermansia and improves liver health in a multi-compartmental obesogenic mice study.  |  Yde, CC., et al. 2021. PLoS One. 16: e0260765. PMID: 34855861
  11. Characterization and functional properties of Maillard reaction products of β-lactoglobulin and polydextrose.  |  Luo, Y., et al. 2022. Food Chem. 377: 131749. PMID: 34990950
  12. Polydextrose Alleviates Adipose Tissue Inflammation and Modulates the Gut Microbiota in High-Fat Diet-Fed Mice.  |  Hu, Q., et al. 2021. Front Pharmacol. 12: 795483. PMID: 35185543
  13. Effect of Polydextrose on the Growth of Pediococcus pentosaceus as Well as Lactic Acid and Bacteriocin-like Inhibitory Substances (BLIS) Production.  |  Wanderley Porto, MC., et al. 2022. Microorganisms. 10: PMID: 36296175
  14. Dietary polydextrose affects the large intestine in rats.  |  Yoshioka, M., et al. 1994. J Nutr. 124: 539-47. PMID: 8145076

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Polydextrose, 25 g

sc-492822
25 g
$76.00

Polydextrose, 100 g

sc-492822A
100 g
$97.00

Polydextrose, 1 kg

sc-492822B
1 kg
$209.00