Molecular structure of Polybrene®, CAS Number: 28728-55-4
Polybrene® (CAS 28728-55-4)
See product citations (1552)
Alternate Names:
Hexadimethrine bromide; 1,5-Dimethyl-1,5-diazaundecamethylene polymethobromide
Application:
Polybrene® is a highly efficient infection reagent used to introduce retroviral vectors into mammalian cells
CAS Number:
28728-55-4
Molecular Weight:
374.20
Molecular Formula:
C13H30Br2N2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Polybrene® is a cationic polymer used to increase the efficiency of infection of certain cells with a retrovirus in cell culture. Polybrene® acts by neutralizing the charge repulsion between the virons and cell surface. It has other uses, including as a peptide carrier for protein sequencing.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Polybrene,[object Object], (CAS 28728-55-4) References
- Protein and peptide separations on high surface area capillaries. | Pesek, JJ., et al. 1999. Electrophoresis. 20: 2343-8. PMID: 10499324
- Compatibility testing without a centrifuge: the slide Polybrene method. | Lin, M. 2004. Transfusion. 44: 410-3. PMID: 14996200
- Method for microfluidic whole-chip temperature measurement using thin-film poly(dimethylsiloxane)/rhodamine B. | Samy, R., et al. 2008. Anal Chem. 80: 369-75. PMID: 18081260
- Conversion of restrictive mouse cells to permissiveness during sequential and mixed double infection by murine leukemia viruses. | Niwa, O., et al. 1976. Virology. 74: 140-53. PMID: 185786
- Coagulant and noncoagulant thrombin enzymatic activity on the endothelium. | Frebelius, S., et al. 1990. Blood Coagul Fibrinolysis. 1: 285-92. PMID: 2103313
- Generation and hepatic differentiation of human iPS cells. | Ishikawa, T., et al. 2012. Methods Mol Biol. 826: 103-14. PMID: 22167643
- Generation of Stable Expression Mammalian Cell Lines Using Lentivirus. | Tandon, N., et al. 2018. Bio Protoc. 8: PMID: 30505888
- Transfection of myeloid cell lines using polybrene/DMSO. | Chisholm, O. and Symonds, G. 1988. Nucleic Acids Res. 16: 2352. PMID: 3357794
- 2-Mercaptoethanol (2-ME)-based IATs or Polybrene method mitigates the interference of daratumumab on blood compatibility tests. | Zhou, Y., et al. 2021. Hematology. 26: 365-370. PMID: 33971806
- Consumption of heparin cofactor II (dermatan sulfate cofactor) and antithrombin during coagulation. | Andersson, TR. 1987. Thromb Res. 46: 355-62. PMID: 3603428
- GAGs-potentiated inhibition of thrombin, factor Xa and plasmin in plasma and in a purified system containing antithrombin III - correlation with total charge density. | Cofrancesco, E., et al. 1981. Thromb Haemost. 46: 749-51. PMID: 6460339
- Measurement of antithrombin III in normal and pathologic states using chromogenic substrate S-2238. Comparison with immunoelectrophoretic and factor Xa inhibition assays. | Goodnight, SH., et al. 1980. Am J Clin Pathol. 73: 639-47. PMID: 7377131
- Strategy for developing microbeads applicable to islet xenotransplantation into a spontaneous diabetic NOD mouse. | Iwata, H., et al. 1994. J Biomed Mater Res. 28: 1201-7. PMID: 7829549
- Histological analysis of microencapsulated dopamine-secreting cells in agarose/poly(styrene sulfonic acid) mixed gel xenotransplanted into the brain. | Miyoshi, Y., et al. 1996. Exp Neurol. 138: 169-75. PMID: 8593892
- A newly developed three-layer agarose microcapsule for a promising biohybrid artificial pancreas: rat to mouse xenotransplantation. | Tun, T., et al. 1996. Cell Transplant. 5: S59-63. PMID: 8889234
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Polybrene® | sc-134220 | 1 ml | $27.00 | |||
Polybrene® | sc-134220A | 50 ml | $265.00 |