Date published: 2025-10-19

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Poly(allylamine hydrochloride) (CAS 71550-12-4)

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Alternate Names:
PAA HCl
CAS Number:
71550-12-4
Molecular Weight:
120,000-200,000
Molecular Formula:
(C3H7N•HCl)n
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Poly(allylamine hydrochloride), or PAH, is a versatile cationic polymer that′s widely studied in materials science for its ability to form electrostatically assembled multilayer films, especially through layer-by-layer deposition with anionic polymers, creating advanced coatings with potential antifouling or antimicrobial properties. Its positive charge is leveraged in nanotechnology for nanoparticle surface modification, enhancing stability and suitability for applications like sensing and targeted drug delivery. In environmental science, Poly(allylamine hydrochloride)′s binding capabilities are applied to the development of novel adsorbents aimed at pollutant removal in water treatment processes. Furthermore, Poly(allylamine hydrochloride)′s utility in fabricating hydrogels is being explored for its potential in tissue engineering, where it contributes to the design of scaffolds that mimic the natural extracellular matrix, highlighting its significance in the synthesis of functional materials tailored for specific applications.


Poly(allylamine hydrochloride) (CAS 71550-12-4) References

  1. Cellular uptake of covalent poly(allylamine hydrochloride) microcapsules and its influences on cell functions.  |  Wang, B., et al. 2012. Macromol Biosci. 12: 1534-45. PMID: 23008194
  2. Targeted Delivery of Docetaxel by Use of Transferrin/Poly(allylamine hydrochloride)-functionalized Graphene Oxide Nanocarrier.  |  Nasrollahi, F., et al. 2016. ACS Appl Mater Interfaces. 8: 13282-93. PMID: 27158834
  3. Poly(allylamine hydrochloride) (PAH) and Bovine Serum Albumin (BSA) Protein Nanostructured as Layer-by-Layer Thin Films.  |  Sa, AWL., et al. 2018. J Nanosci Nanotechnol. 18: 3908-3915. PMID: 29442726
  4. Salinity Gradient Energy from Expansion and Contraction of Poly(allylamine hydrochloride) Hydrogels.  |  Bui, TQ., et al. 2018. ACS Appl Mater Interfaces. 10: 22218-22225. PMID: 29883097
  5. Poly-allylamine hydrochloride and fucoidan-based self-assembled polyelectrolyte complex nanoparticles for cancer therapeutics.  |  Wang, P., et al. 2019. J Biomed Mater Res A. 107: 339-347. PMID: 30548527
  6. Poly(allylamine hydrochloride)-functionalized reduced graphene oxide for synergistic chemo-photothermal therapy.  |  Roy, S., et al. 2019. Nanomedicine (Lond). 14: 255-274. PMID: 30676277
  7. Synthetic sulfonated derivatives of poly(allylamine hydrochloride) as inhibitors of human metapneumovirus.  |  Ciejka, J., et al. 2019. PLoS One. 14: e0214646. PMID: 30921418
  8. Poly-(allylamine hydrochloride)-coated but not poly(acrylic acid)-coated upconversion nanoparticles induce autophagy and apoptosis in human blood cancer cells.  |  Juan, J., et al. 2015. J Mater Chem B. 3: 5769-5776. PMID: 32262573
  9. Highly efficient and ultrafast removal of Cr(VI)in aqueous solution to ppb level by poly(allylamine hydrochloride) covalently cross-linked amino-modified graphene oxide.  |  Bao, S., et al. 2021. J Hazard Mater. 409: 124470. PMID: 33189464
  10. Tuning the Surface Properties of Poly(Allylamine Hydrochloride)-Based Multilayer Films.  |  Ciejka, J., et al. 2021. Materials (Basel). 14: PMID: 34062785
  11. Novel Core-Shell Polyamine Phosphate Nanoparticles Self-Assembled from PEGylated Poly(allylamine hydrochloride) with Low Toxicity and Increased In Vivo Circulation Time.  |  Andreozzi, P., et al. 2021. Small. 17: e2102211. PMID: 34278713
  12. A Novel Amperometric Biosensor Based on Poly(allylamine hydrochloride) for Determination of Ethanol in Beverages.  |  Istrate, OM., et al. 2021. Sensors (Basel). 21: PMID: 34640829
  13. Electric Potential of Citrate-Capped Gold Nanoparticles Is Affected by Poly(allylamine hydrochloride) and Salt Concentration.  |  Wei, X., et al. 2022. ACS Appl Mater Interfaces. 14: 12538-12550. PMID: 35230798
  14. A poly(allylamine hydrochloride)/poly(styrene sulfonate) microcapsule-coated cotton fabric for stimulus-responsive textiles.  |  Zhao, Z., et al. 2020. RSC Adv. 10: 17731-17738. PMID: 35515608
  15. The influence of poly(allylamine hydrochloride) hydrogel crosslinking density on its thermal and phosphate binding properties.  |  Elsiddig, R., et al. 2022. Int J Pharm. 621: 121806. PMID: 35526696

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Poly(allylamine hydrochloride), 10 g

sc-280000
10 g
$194.00