Polaprezinc (CAS 107667-60-7)
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Polaprezinc, a coordination compound consisting of zinc and the amino acid derivative carnosine, is widely researched in the context of cellular protection and antioxidative properties. This compound is of particular interest in the field of gastroenterology research, where its ability to protect gastrointestinal mucosa from oxidative stress is investigated. In the study of cellular biology, polaprezinc is utilized to understand the mechanisms of cellular defense against reactive oxygen species and its potential to stabilize cell membranes and DNA. In nutritional science, the bioavailability and pathways of zinc absorption facilitated by the carnosine ligand are topics of investigation, shedding light on mineral supplementation strategies. Moreover, polaprezinc′s contribution to wound healing processes at the cellular level is also a subject of study, particularly its impact on collagen synthesis and cell proliferation.
Polaprezinc (CAS 107667-60-7) References
- Polaprezinc (N-(3-aminopropionyl)-L-histidinato zinc) ameliorates dextran sulfate sodium-induced colitis in mice. | Ohkawara, T., et al. 2005. Scand J Gastroenterol. 40: 1321-7. PMID: 16334442
- Polaprezinc attenuates liver fibrosis in a mouse model of non-alcoholic steatohepatitis. | Sugino, H., et al. 2008. J Gastroenterol Hepatol. 23: 1909-16. PMID: 18422963
- Polaprezinc prevents ongoing thioacetamide-induced liver fibrosis in rats. | Kono, T., et al. 2012. Life Sci. 90: 122-30. PMID: 22100444
- [Development of polaprezinc research]. | Takei, M. 2012. Yakugaku Zasshi. 132: 271-7. PMID: 22382829
- Polaprezinc attenuates cyclophosphamide-induced cystitis and related bladder pain in mice. | Murakami-Nakayama, M., et al. 2015. J Pharmacol Sci. 127: 223-8. PMID: 25727961
- Polaprezinc inhibits liver fibrosis and proliferation in hepatocellular carcinoma. | Ye, J., et al. 2017. Mol Med Rep. 16: 5523-5528. PMID: 28849143
- Utility of polaprezinc in reducing toxicities during radiotherapy: a literature review. | Doi, H., et al. 2018. Future Oncol. 14: 1977-1988. PMID: 30074413
- Protective effect of polaprezinc on acute gastric mucosal injury in rats. | Zhang, Q. and Feng, L. 2019. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 44: 22-27. PMID: 30837398
- Protective effect of polaprezinc on cadmium-induced injury of lung epithelium. | Kimura, K., et al. 2019. Metallomics. 11: 1310-1320. PMID: 31236550
- Recent advances on polaprezinc for medical use (Review). | Li, M., et al. 2021. Exp Ther Med. 22: 1445. PMID: 34721687
- Drug repositioning of polaprezinc for bone fracture healing. | Ko, EA., et al. 2022. Commun Biol. 5: 462. PMID: 35577977
- Protective Effect of Polaprezinc and Hyperbaric Oxygen Therapy on Radiation-induced Small Intestinal Damage in Mice. | Suzuki, H., et al. 2022. In Vivo. 36: 2218-2223. PMID: 36099093
- Efficacy and Safety of Polaprezinc-Based Therapy versus the Standard Triple Therapy for Helicobacter pylori Eradication: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. | Mahmoud, A., et al. 2022. Nutrients. 14: PMID: 36235778
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Polaprezinc, 100 mg | sc-208179 | 100 mg | $342.00 |