PNU 96415E CAS: 170856-41-4
MF: C21H25FN2O•2HCl
MW: 413.36
A SR-2A inhibitor.

PNU 96415E (CAS 170856-41-4)

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Alternate Names: 1-[2-(3,4-dihydro-1H-2-benzopyran-1-yl)ethyl]-4-(4-fluorophenyl)piperazine dihydrochloride
Application: PNU 96415E is a SR-2A inhibitor
CAS Number: 170856-41-4
Purity: ≥98%
Molecular Weight: 413.36
Molecular Formula: C21H25FN2O•2HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

PNU 96415E is chemically unrelated to clozapine, an antipsychotic agent. PNU 96415E displays highest affinity for dopamine D4 and SR-2A and relatively weak affinity at D2 receptors (Ki values are 3.0, 5.8, 134, 181, 199, 240, 411 and > 678 nM for D4, SR-2A, SR-1A, α1, D2, D3, D1, α2 and muscarinic receptors respectively).


References

1. Tang, A.H., et al. 1997. J. Pharmacol. Exp. Ther. 281: 440-447. PMID: 9103528
2. Goudie, A.J., et al. 1998. Behav Pharmacol. 9: 699-710. PMID: 9890260

Physical State :
Solid
Solubility :
Soluble to 10 mM in Water
Storage :
Desiccate at room temperature
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
9909647
SMILES :
C1COC(C2=CC=CC=C21)CCN3CCN(CC3)C4=CC=C(C=C4)F.Cl.Cl

Download SDS (MSDS)

Certificate of Analysis

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