(+)-SKF 10047 hydrochloride (CAS 133005-41-1)
Available in US only.
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(+)-SKF 10047 hydrochloride is a compound that has been the subject of research primarily in the field of neuroscience. This compound is known to act as a sigma receptor agonist, and studies involving (+)-SKF 10047 hydrochloride often aim to elucidate the function of sigma receptors in the brain. It is used to explore the involvement of these receptors in modulating neurotransmission, neuroprotection, and neuroplasticity. Additionally, the compound is applied in research to determine the potential role of sigma receptor activation in modulating the effects of other neurotransmitter systems. Research with (+)-SKF 10047 hydrochloride also includes investigations into its influence on ion channel activity and the resulting implications for cellular signaling pathways.
(+)-SKF 10047 hydrochloride (CAS 133005-41-1) References
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- Phencyclidine impairs latent learning in mice: interaction between glutamatergic systems and sigma(1) receptors. | Noda, A., et al. 2001. Neuropsychopharmacology. 24: 451-60. PMID: 11182540
- Inhibition of hyperpolarization-activated cation currents by phencyclidine and some sigma ligands in rat hippocampal CA1 pyramidal neurons in vitro. | Tanabe, M. 2007. Neuropharmacology. 53: 406-14. PMID: 17631922
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- Sequential cytoprotective responses to Sigma1 ligand-induced endoplasmic reticulum stress. | Schrock, JM., et al. 2013. Mol Pharmacol. 84: 751-62. PMID: 24006496
- Interaction of the discriminative stimulus effects of phencyclidine with those of (+)-N-allylnormetazocine, pentobarbital and d-amphetamine. | McMillan, DE. and Wessinger, WD. 1989. Pharmacol Biochem Behav. 32: 711-5. PMID: 2740424
- Differential stereospecific effects of mu, kappa, and sigma opioid agonists on cortical EEG power spectra in the rat. | Young, GA. and Khazan, N. 1983. NIDA Res Monogr. 43: 190-5. PMID: 6308453
- Further characterization of [3H]ifenprodil binding to sigma receptors in rat brain. | Hashimoto, K. and London, ED. 1993. Eur J Pharmacol. 236: 159-63. PMID: 8319742
- Involvement of sigma 1 receptor in (+)-N-allylnormetazocine-stimulated hippocampal cholinergic functions in rats. | Matsuno, K., et al. 1995. Brain Res. 690: 200-6. PMID: 8535837
- (+)-SKF-10,047 and dextromethorphan ameliorate conditioned fear stress via dopaminergic systems linked to phenytoin-regulated sigma 1 sites. | Kamei, H., et al. 1996. Eur J Pharmacol. 309: 149-58. PMID: 8874133
- The effects of morphine- and nalorphine- like drugs in the nondependent and morphine-dependent chronic spinal dog. | Martin, WR., et al. 1976. J Pharmacol Exp Ther. 197: 517-32. PMID: 945347
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(+)-SKF 10047 hydrochloride, 10 mg | sc-204282 | 10 mg | $454.00 | |||
| US: Only available in the US | ||||||
(+)-SKF 10047 hydrochloride, 50 mg | sc-204282A | 50 mg | $1637.00 | |||
| US: Only available in the US | ||||||