Date published: 2025-12-7

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(±) trans-2,5-Bis(3,4,5-trimethoxyphenyl)-1,3-dioxolane (CAS 116673-45-1)

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Alternate Names:
trans-BTP Dioxolane
Application:
CAS Number:
116673-45-1
Molecular Weight:
406.4
Molecular Formula:
C21H26O8
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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(±) trans-2,5-Bis(3,4,5-trimethoxyphenyl)-1,3-dioxolane is a selective and potent PAF-R (platelet activating factor receptor) antagonist of the diaryl tetrahydrofuran class. It has been reported to block LTP in field CA1 in rat hippocampus.


(±) trans-2,5-Bis(3,4,5-trimethoxyphenyl)-1,3-dioxolane (CAS 116673-45-1) References

  1. Inverse agonist activity of selected ligands of platelet-activating factor receptor.  |  Dupré, DJ., et al. 2001. J Pharmacol Exp Ther. 299: 358-65. PMID: 11561099
  2. Platelet-activating factor secreted by DDAVP-treated monocytes mediates von Willebrand factor release from endothelial cells.  |  Hashemi, S., et al. 1993. J Cell Physiol. 154: 496-505. PMID: 8436598

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(±) trans-2,5-Bis(3,4,5-trimethoxyphenyl)-1,3-dioxolane, 1 mg

sc-201029
1 mg
$62.00

(±) trans-2,5-Bis(3,4,5-trimethoxyphenyl)-1,3-dioxolane, 5 mg

sc-201029A
5 mg
$309.00