Date published: 2025-12-6

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(±)-Taxifolin (CAS 480-18-2)

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Alternate Names:
(±)-Dihydroquercetin
Application:
(±)-Taxifolin is a flavonoid small molecule with antioxidant effects
CAS Number:
480-18-2
Purity:
≥90%
Molecular Weight:
304.25
Molecular Formula:
C15H12O7
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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(±)-Taxifolin is a flavonoid compound that functions as an antioxidant in experimental applications. It exerts its mechanism of action by scavenging free radicals and preventing oxidative damage to cellular components. (±)-Taxifolin is known to inhibit lipid peroxidation and protect against DNA damage caused by reactive oxygen species. (±)-Taxifolin may act to chelate metal ions, thereby reducing their ability to catalyze oxidative reactions. Its ability to modulate cellular redox status may be a useful for studying oxidative stress and its impact on biological systems. (±)-Taxifolin regulates various signaling pathways involved in inflammation and cell survival, contributing to its role in experimental research. (±)-Taxifolin plays a functional role in investigating the mechanisms of oxidative stress and cellular signaling pathways, making it useful for understanding the impact of these processes on biological systems.


(±)-Taxifolin (CAS 480-18-2) References

  1. Modulation of hepatic lipoprotein synthesis and secretion by taxifolin, a plant flavonoid.  |  Theriault, A., et al. 2000. J Lipid Res. 41: 1969-79. PMID: 11108730
  2. Inhibitory activity of diacylglycerol acyltransferase (DGAT) and microsomal triglyceride transfer protein (MTP) by the flavonoid, taxifolin, in HepG2 cells: potential role in the regulation of apolipoprotein B secretion.  |  Casaschi, A., et al. 2004. Atherosclerosis. 176: 247-53. PMID: 15380446
  3. An insight into the health-promoting effects of taxifolin (dihydroquercetin).  |  Sunil, C. and Xu, B. 2019. Phytochemistry. 166: 112066. PMID: 31325613
  4. 7-O-Esters of taxifolin with pronounced and overadditive effects in neuroprotection, anti-neuroinflammation, and amelioration of short-term memory impairment in vivo.  |  Gunesch, S., et al. 2020. Redox Biol. 29: 101378. PMID: 31926632
  5. Taxifolin ameliorate high-fat-diet feeding plus acute ethanol binge-induced steatohepatitis through inhibiting inflammatory caspase-1-dependent pyroptosis.  |  Zhan, ZY., et al. 2021. Food Funct. 12: 362-372. PMID: 33325949
  6. Taxifolin: A Potential Therapeutic Agent for Cerebral Amyloid Angiopathy.  |  Saito, S., et al. 2021. Front Pharmacol. 12: 643357. PMID: 33643053
  7. Pharmacological basis and new insights of taxifolin: A comprehensive review.  |  Das, A., et al. 2021. Biomed Pharmacother. 142: 112004. PMID: 34388527
  8. Exploring the Molecular Mechanism of Action of Yinchen Wuling Powder for the Treatment of Hyperlipidemia, Using Network Pharmacology, Molecular Docking, and Molecular Dynamics Simulation.  |  Ye, J., et al. 2021. Biomed Res Int. 2021: 9965906. PMID: 34746316
  9. Taxifolin Alleviates DSS-Induced Ulcerative Colitis by Acting on Gut Microbiome to Produce Butyric Acid.  |  Li, W., et al. 2022. Nutrients. 14: PMID: 35268045
  10. Interaction of flavonoids with ascorbate and determination of their univalent redox potentials: a pulse radiolysis study.  |  Bors, W., et al. 1995. Free Radic Biol Med. 19: 45-52. PMID: 7635358
  11. Suppression of hydroperoxide-induced cytotoxicity by polyphenols.  |  Nakayama, T. 1994. Cancer Res. 54: 1991s-1993s. PMID: 8137326
  12. Suppression of active oxygen-induced cytotoxicity by flavonoids.  |  Nakayama, T., et al. 1993. Biochem Pharmacol. 45: 265-7. PMID: 8381006
  13. Structure-antioxidant activity relationships of flavonoids and phenolic acids.  |  Rice-Evans, CA., et al. 1996. Free Radic Biol Med. 20: 933-56. PMID: 8743980

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(±)-Taxifolin, 10 mg

sc-202828
10 mg
$51.00

(±)-Taxifolin, 50 mg

sc-202828A
50 mg
$154.00

(±)-Taxifolin, 100 mg

sc-202828B
100 mg
$286.00

(±)-Taxifolin, 500 mg

sc-202828C
500 mg
$459.00