(±)-Piperazine-2-carboxylic acid dihydrochloride (CAS 3022-15-9)
QUICK LINKS
(±)-Piperazine-2-carboxylic acid dihydrochloride plays a role in laboratory experiments. This organic compound consists of two hydrogen atoms, two nitrogen atoms, and two chlorine atoms, forming a white, crystalline solid. (±)-Piperazine-2-carboxylic acid dihydrochloride exhibits insolubility in water while being soluble in ethanol and methanol. (±)-Piperazine-2-carboxylic acid dihydrochloride is widely recognized for its valuable contributions to scientific research. Moreover, it facilitates the synthesis of various organic compounds such as amino acids, peptides, and nucleosides. Additionally, PPCD acts as a catalyst in polymer synthesis and finds utility in the synthesis of a wide range of other organic compounds. The precise mechanism of action for (±)-Piperazine-2-carboxylic acid dihydrochloride is not yet fully elucidated. It is believed to exhibit acid-like behavior in the presence of water and is thought to participate in hydrogen bond formation.
(±)-Piperazine-2-carboxylic acid dihydrochloride (CAS 3022-15-9) References
- Design and synthesis of piperazine-based matrix metalloproteinase inhibitors. | Cheng, M., et al. 2000. J Med Chem. 43: 369-80. PMID: 10669564
- Solid-phase synthesis of libraries generated from a 4-phenyl-2-carboxy-piperazine scaffold. | Nilsson, JW., et al. 2001. J Comb Chem. 3: 546-53. PMID: 11703150
- Innovative cationic fullerenes as broad-spectrum light-activated antimicrobials. | Huang, L., et al. 2010. Nanomedicine. 6: 442-52. PMID: 19914400
- Unique selectivity windows using selective displacers/eluents and mobile phase modifiers on hydroxyapatite. | Morrison, CJ., et al. 2010. J Chromatogr A. 1217: 6484-95. PMID: 20832806
- Antimicrobial Photodynamic Therapy with Functionalized Fullerenes: Quantitative Structure-activity Relationships. | Mizuno, K., et al. 2011. J Nanomed Nanotechnol. 2: 1-9. PMID: 21743839
- Synthesis of decacationic [60]fullerene decaiodides giving photoinduced production of superoxide radicals and effective PDT-mediation on antimicrobial photoinactivation. | Wang, M., et al. 2013. Eur J Med Chem. 63: 170-84. PMID: 23474903
- Single-walled carbon nanotubes functionalized with aptamer and piperazine-polyethylenimine derivative for targeted siRNA delivery into breast cancer cells. | Mohammadi, M., et al. 2015. Int J Pharm. 485: 50-60. PMID: 25712164
- Heterocyclic amine-modified polyethylenimine as gene carriers for transfection of mammalian cells. | Salmasi, Z., et al. 2015. Eur J Pharm Biopharm. 96: 76-88. PMID: 26209125
- Gene delivery efficiency and cytotoxicity of heterocyclic amine-modified PAMAM and PPI dendrimers. | Hashemi, M., et al. 2016. Mater Sci Eng C Mater Biol Appl. 61: 791-800. PMID: 26838910
- Polyethylenimine: A versatile, multifunctional non-viral vector for nucleic acid delivery. | Pandey, AP. and Sawant, KK. 2016. Mater Sci Eng C Mater Biol Appl. 68: 904-918. PMID: 27524093
- Effective and safe in vivo gene delivery based on polyglutamic acid complexes with heterocyclic amine modified-polyethylenimine. | Salmasi, Z., et al. 2018. Colloids Surf B Biointerfaces. 172: 790-796. PMID: 30268055
- Bis(vinylsulfonyl)piperazines as efficient linkers for highly homogeneous antibody-drug conjugates. | Huang, R., et al. 2020. Eur J Med Chem. 190: 112080. PMID: 32018094
- A pH- and Bioreducible Cationic Copolymer with Amino Acids and Piperazines for Adenovirus Delivery. | Thambi, T., et al. 2022. Pharmaceutics. 14: PMID: 35335972
- Revisiting of Properties and Modified Polyethylenimine-Based Cancer Gene Delivery Systems. | Mohammadi, N., et al. 2023. Biochem Genet.. PMID: 37394575
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(±)-Piperazine-2-carboxylic acid dihydrochloride, 5 g | sc-255428 | 5 g | $61.00 |