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(±)-Epinephrine hydrochloride (CAS 329-63-5)

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Alternate Names:
(+-)-Adrenaline hydrochloride; (±)-Adrenalin, 4-(1-Hydroxy-2-[methylamino]ethyl)-1,2-benzenediol hydrochloride
Application:
(±)-Epinephrine hydrochloride is an adrenergic receptor agonist
CAS Number:
329-63-5
Purity:
≥98%
Molecular Weight:
219.67
Molecular Formula:
C9H13NO3•HCl
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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(±)-Epinephrine hydrochloride, also known as racemic epinephrine, is a synthetic combination of two stereoisomers of epinephrine. This compound is a racemic mixture of Levo-epinephrine and Dextro-epinephrine, two isomers of epinephrine. The mechanism of action of (±)-Epinephrine hydrochloride involves the activation of the β-adrenergic receptor, present in the lungs, heart, and other organs.


(±)-Epinephrine hydrochloride (CAS 329-63-5) References

  1. Treatment of laryngotracheobronchitis (croup). Use of intermittent positive-pressure breathing and racemic epinephrine.  |  Taussig, LM., et al. 1975. Am J Dis Child. 129: 790-3. PMID: 1096594
  2. Primary and secondary leucocyte changes following the intramuscular injection of epinephrine hydrochloride.  |  SAMUELS, AJ. 1951. J Clin Invest. 30: 941-7. PMID: 14880622
  3. Allergic reaction to epinephrine preparation in 2% lidocaine: two case reports.  |  Kohase, H. and Umino, M. 2004. Anesth Prog. 51: 134-7. PMID: 15675262
  4. Combined preoperative topical atropine sulfate 1% and intracameral nonpreserved epinephrine hydrochloride 1:4000 [corrected] for management of intraoperative floppy-iris syndrome.  |  Masket, S. and Belani, S. 2007. J Cataract Refract Surg. 33: 580-2. PMID: 17397728
  5. Effect of maxillary sinus packing with epinephrine hydrochloride-soaked cotton pledgets on complications after canine fossa puncture.  |  Byun, JY. and Lee, JY. 2014. Acta Otolaryngol. 134: 300-6. PMID: 24359098
  6. Investigation on the enantiomeric impurity of epinephrine hydrochloride injections.  |  Yang, ZY. and Xu, RZ. 1989. Chirality. 1: 92-3. PMID: 2642039
  7. Development of a fast dissolving film of epinephrine hydrochloride as a potential anaphylactic treatment for pediatrics.  |  Alayoubi, A., et al. 2017. Pharm Dev Technol. 22: 1012-1016. PMID: 26740126
  8. Pupil Dilation with Intracameral Epinephrine Hydrochloride during Phacoemulsification and Intraocular Lens Implantation.  |  Yu, AY., et al. 2016. J Ophthalmol. 2016: 4917659. PMID: 26904274
  9. The effect of epinephrine and benzalkonium chloride on cultured corneal endothelial and trabecular meshwork cells.  |  Samples, JR., et al. 1989. Exp Eye Res. 49: 1-12. PMID: 2759185
  10. Extended Stability of Epinephrine Hydrochloride Injection in Polyvinyl Chloride Bags Stored in Amber Ultraviolet Light-Blocking Bags.  |  Van Matre, ET., et al. 2017. Hosp Pharm. 52: 570-573. PMID: 29276291
  11. The effect of topical epinephrine hydrochloride in saline on blood loss following tangential excision of burn wounds.  |  Snelling, CF. and Shaw, K. 1983. Plast Reconstr Surg. 72: 830-6. PMID: 6647606
  12. Immediate effect of epinephrine on aqueous formation in the normal human eye as measured by fluorophotometry.  |  Townsend, DJ. and Brubaker, RF. 1980. Invest Ophthalmol Vis Sci. 19: 256-66. PMID: 7358476
  13. Contact allergy to ophthalmic dipivalyl epinephrine hydrochloride: demonstration by patch testing.  |  Gaspari, AA. 1993. Contact Dermatitis. 28: 35-7. PMID: 8428443
  14. Stability of epinephrine hydrochloride in an extemporaneously compounded topical anesthetic solution of lidocaine, racepinephrine, and tetracaine.  |  Larson, TA., et al. 1996. Am J Health Syst Pharm. 53: 659-62. PMID: 8800972
  15. Stability of high-concentration dopamine hydrochloride, norepinephrine bitartrate, epinephrine hydrochloride, and nitroglycerin in 5% dextrose injection.  |  Peddicord, TE., et al. 1997. Am J Health Syst Pharm. 54: 1417-9. PMID: 9194988

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(±)-Epinephrine hydrochloride, 5 g

sc-252780
5 g
$82.00

(±)-Epinephrine hydrochloride, 25 g

sc-252780A
25 g
$337.00

(±)-Epinephrine hydrochloride, 1 kg

sc-252780B
1 kg
$7140.00