Date published: 2025-10-2

1-800-457-3801

SCBT Portrait Logo
Seach Input

(±)-Carnitine hydrochloride (CAS 461-05-2)

0.0(0)
Write a reviewAsk a question

Alternate Names:
β-Hydroxy-γ-(trimethylammonio)butyrate hydrochloride; (±)-Carnitine chloride; DL-Carnitine hydrochloride
Application:
(±)-Carnitine hydrochloride is a compound involved in the metabolism of fatty acids
CAS Number:
461-05-2
Purity:
≥98%
Molecular Weight:
197.66
Molecular Formula:
C5H10ClNO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

(±)-Carnitine hydrochloride plays a role in the transport of fatty acids into the mitochondria for energy production. It functions by facilitating the entry of long-chain fatty acids into the mitochondrial matrix, where they undergo beta-oxidation to generate ATP. (±)-Carnitine Hydrochloride acts as a carrier molecule, binding to fatty acids and transporting them across the mitochondrial membrane. Once inside the mitochondria, (±)-Carnitine hydrochloride releases the fatty acids, allowing them to undergo oxidation and produce energy. This process is necessary for the metabolism of fatty acids and the production of cellular energy. By facilitating the transport of fatty acids, (±)-Carnitine hydrochloride contributes to the overall energy balance within the cell, supporting various metabolic processes. Its role in fatty acid metabolism may be an important component in cellular energy production and metabolic regulation.


(±)-Carnitine hydrochloride (CAS 461-05-2) References

  1. Plasma acylcarnitine profiles suggest incomplete long-chain fatty acid beta-oxidation and altered tricarboxylic acid cycle activity in type 2 diabetic African-American women.  |  Adams, SH., et al. 2009. J Nutr. 139: 1073-81. PMID: 19369366
  2. Rat adipose-tissue glycerol phosphate acyltransferase can be inactivated by cyclic AMP-dependent protein kinase.  |  Nimmo, HG. and Houston, B. 1978. Biochem J. 176: 607-10. PMID: 217367
  3. Measurement of acylcarnitine substrate to product ratios specific to biotin-dependent carboxylases offers a combination of indicators of biotin status in humans.  |  Bogusiewicz, A., et al. 2012. J Nutr. 142: 1621-5. PMID: 22833654
  4. [Pharmacologic influencing of fetal phospholipide synthesis. Part II: Carnitin - a new way of dyspnea syndrome prophylaxis? (author's transl)].  |  Lohninger, A., et al. 1978. Z Geburtshilfe Perinatol. 182: 29-37. PMID: 246640
  5. In HepG2 cells, coexisting carnitine deficiency masks important indicators of marginal biotin deficiency.  |  Bogusiewicz, A., et al. 2015. J Nutr. 145: 32-40. PMID: 25527659
  6. Differential mobility spectrometry (DMS) reveals the elevation of urinary acetylcarnitine in non-human primates (NHPs) exposed to radiation.  |  Vera, NB., et al. 2018. J Mass Spectrom. 53: 548-559. PMID: 29596720
  7. Histidine is selectively required for the growth of Myc-dependent dedifferentiation tumours in the Drosophila CNS.  |  Froldi, F., et al. 2019. EMBO J. 38: PMID: 30804004
  8. Differences in Fatty Acid Oxidation between Nab-Paclitaxel- and Solvent-Based Paclitaxel-Treated A549 Cells Based on Metabolomics.  |  Huang, JW., et al. 2021. ACS Omega. 6: 5138-5145. PMID: 33681555
  9. Cell metabolomics analyses revealed a role of altered fatty acid oxidation in neurotoxicity pattern difference between nab-paclitaxel and solvent-based paclitaxel.  |  Huang, JW., et al. 2021. PLoS One. 16: e0248942. PMID: 33740022
  10. The hepatic compensatory response to elevated systemic sulfide promotes diabetes.  |  Carter, RN., et al. 2021. Cell Rep. 37: 109958. PMID: 34758301
  11. 25.24%-Efficiency FACsPbI3 Perovskite Solar Cells Enabled by Intermolecular Esterification Reaction of DL-Carnitine Hydrochloride.  |  Yang, L., et al. 2023. Adv Mater. 35: e2211545. PMID: 36731421
  12. Pharmacokinetics of l-carnitine in man following intravenous infusion of dl-carnitine.  |  Welling, PG., et al. 1979. Int J Clin Pharmacol Biopharm. 17: 56-60. PMID: 422302
  13. pH-dependence of carnitine acetyltransferase activity.  |  Chase, JF. 1967. Biochem J. 104: 503-9. PMID: 6048792
  14. [Examination of plasminogen-activators and plasmin-inhibitors in maternal and fetal rat-lung-tissue after administration of DL-carnitine-hydrochloride (author's transl)].  |  Hückmann, T., et al. 1980. Z Geburtshilfe Perinatol. 184: 54-9. PMID: 6894511

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(±)-Carnitine hydrochloride, 5 g

sc-255011
5 g
$20.00

(±)-Carnitine hydrochloride, 25 g

sc-255011A
25 g
$26.00