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(±)-α-Tocopherol nicotinate (CAS 51898-34-1)

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Alternate Names:
VitaminE nicotinate; Renascin; tocopherol nicotinate
CAS Number:
51898-34-1
Molecular Weight:
535.80
Molecular Formula:
C35H53NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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(±)-α-Tocopherol nicotinate is a derivative of vitamin E and niacin. (±)-α-Tocopherol nicotinate is a red-orange crystalline solid with high solubility in water. It is sensitive to reactions with acids and bases, and upon hydrolysis, it releases niacin moiety. The compound is known for its ability to decrease lipid peroxidation and offer protection from oxidative stress.


(±)-α-Tocopherol nicotinate (CAS 51898-34-1) References

  1. [Effects of alpha-tocopherol nicotinate in hyperbaric oxygen intoxication].  |  Okamoto, H. and Isa, T. 1975. Masui. 24: 468-71. PMID: 1172020
  2. In vitro evaluation of inhibitory effects of antidiabetic and antihyperlipidemic drugs on human carboxylesterase activities.  |  Fukami, T., et al. 2010. Drug Metab Dispos. 38: 2173-8. PMID: 20810539
  3. UPLC method for the determination of vitamin E homologues and derivatives in vegetable oils, margarines and supplement capsules using pentafluorophenyl column.  |  Wong, YF., et al. 2014. Talanta. 130: 299-306. PMID: 25159413
  4. Oxidative profiling of the failing right heart in rats with pulmonary hypertension.  |  Wang, X., et al. 2017. PLoS One. 12: e0176887. PMID: 28472095
  5. Effects of alpha-tocopherol-nicotinate administration on the microdynamics of phospholipids of erythrocyte membranes in human subjects.  |  Koyama, T. and Araiso, T. 1988. J Nutr Sci Vitaminol (Tokyo). 34: 449-57. PMID: 3230416
  6. Simultaneous analysis of retinol, six carotenoids, two tocopherols, and coenzyme Q10 from human plasma by HPLC.  |  Boulet, L., et al. 2020. J Chromatogr B Analyt Technol Biomed Life Sci. 1151: 122158. PMID: 32531701
  7. Two-dimensional high-performance liquid chromatographic system for the direct determination of tocopherol derivatives in plasma.  |  Ijitsu, T., et al. 1988. J Chromatogr. 427: 29-39. PMID: 3410903
  8. In Silico Evaluation of Enzymatic Tunnels in the Biotransformation of α-Tocopherol Esters.  |  Azevedo, TSM., et al. 2021. Front Bioeng Biotechnol. 9: 805059. PMID: 35127674
  9. Antiarrhythmic activity of alpha-tocopherol nicotinate and related compounds and their physico-chemical properties.  |  Schlieper, P. and Tawfik, H. 1987. Arzneimittelforschung. 37: 920-3. PMID: 3675687
  10. [Clinical studies on the physical capacity of aged persons following the administration of alpha-tocopherol-nicotinate].  |  Böhlau, V. 1971. Arzneimittelforschung. 21: 674-6. PMID: 5109692

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(±)-α-Tocopherol nicotinate, 5 g

sc-216078
5 g
$66.00

(±)-α-Tocopherol nicotinate, 25 g

sc-216078A
25 g
$148.00