Date published: 2026-4-4

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(±)-α-Methylbenzylamine (CAS 618-36-0)

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Alternate Names:
(±)-α-Methylbenzylamine; alpha-Methylbenzylamine; (±)-1-Phenylethylamine
CAS Number:
618-36-0
Purity:
≥98%
Molecular Weight:
121.18
Molecular Formula:
C8H11N
Supplemental Information:
This is as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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(±)-α-Methylbenzylamine is an organic compound categorized as an alkylamine. Present in minute quantities in certain plants, as well as in some foods, it serves as a precursor for various essential compounds, notably the neurotransmitter dopamine and the hormone epinephrine. Beyond its natural occurrence, (±)-α-Methylbenzylamine finds extensive applications in scientific research. In the realm of scientific investigation, (±)-α-Methylbenzylamine plays a pivotal role in the synthesis of other substances like neurotransmitters and hormones. Furthermore, it serves as a substrate for enzyme reactions, such as facilitating the conversion of tyrosine into dopamine. (±)-α-Methylbenzylamine boasts diverse applications in scientific exploration, showcasing its significance in the synthesis of vital compounds.


(±)-α-Methylbenzylamine (CAS 618-36-0) References

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  2. Deracemization of alpha-methylbenzylamine using an enzyme obtained by in vitro evolution.  |  Alexeeva, M., et al. 2002. Angew Chem Int Ed Engl. 41: 3177-80. PMID: 12207381
  3. Simultaneous synthesis of enantiomerically pure (R)-1-phenylethanol and (R)-alpha-methylbenzylamine from racemic alpha-methylbenzylamine using omega-transaminase/alcohol dehydrogenase/glucose dehydrogenase coupling reaction.  |  Yun, H., et al. 2003. Biotechnol Lett. 25: 809-14. PMID: 12882012
  4. A study of the liquid and solvent properties of optically active and racemic alpha-methylbenzylamine.  |  Fischer, AT., et al. 2007. J Phys Chem B. 111: 8187-96. PMID: 17583940
  5. Simple protocols for NMR analysis of the enantiomeric purity of chiral diols.  |  Kelly, AM., et al. 2008. Nat Protoc. 3: 215-9. PMID: 18274523
  6. Rapid and sensitive kinetic assay for characterization of omega-transaminases.  |  Schätzle, S., et al. 2009. Anal Chem. 81: 8244-8. PMID: 19739593
  7. Three-component chiral derivatizing protocols for NMR spectroscopic enantiodiscrimination of hydroxy acids and primary amines.  |  Chaudhari, SR. and Suryaprakash, N. 2012. J Org Chem. 77: 648-51. PMID: 22145800
  8. ω-Transaminase from Ochrobactrum anthropi is devoid of substrate and product inhibitions.  |  Park, ES. and Shin, JS. 2013. Appl Environ Microbiol. 79: 4141-4. PMID: 23584786
  9. Natural product derived antiprotozoal agents: synthesis, biological evaluation, and structure-activity relationships of novel chromene and chromane derivatives.  |  Harel, D., et al. 2013. J Med Chem. 56: 7442-8. PMID: 23968432
  10. Tailoring D-amino acid oxidase from the pig kidney to R-stereoselective amine oxidase and its use in the deracemization of α-methylbenzylamine.  |  Yasukawa, K., et al. 2014. Angew Chem Int Ed Engl. 53: 4428-31. PMID: 24644036
  11. Looking Inside the Intramolecular C-H∙∙∙O Hydrogen Bond in Lactams Derived from α-Methylbenzylamine.  |  Mejía, S., et al. 2017. Molecules. 22: PMID: 28264508
  12. Self-Assembly of Peptide Chiral Nanostructures with Sequence-Encoded Enantioseparation Capability.  |  Fan, Y., et al. 2020. Langmuir. 36: 10361-10370. PMID: 32787008
  13. Construction and Application of Graphene Oxide-Bovine Serum Albumin Modified Extended Gate Field Effect Transistor Chiral Sensor.  |  Li, L., et al. 2021. Sensors (Basel). 21: PMID: 34200213
  14. Studies of monoamine oxidase and semicarbazide-sensitive amine oxidase. II. Inhibition by alpha-methylated substrate-analogue monoamines, alpha-methyltryptamine, alpha-methylbenzylamine and two enantiomers of alpha-methylbenzylamine.  |  Arai, Y., et al. 1986. Jpn J Pharmacol. 41: 191-7. PMID: 3747266
  15. Probes of the active site of norepinephrine N-methyltransferase: effect of hydrophobic and hydrophilic interactions on side-chain binding of amphetamine and alpha-methylbenzylamine.  |  Grunewald, GL., et al. 1982. J Med Chem. 25: 1248-50. PMID: 7143366

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(±)-α-Methylbenzylamine, 25 ml

sc-239163
25 ml
$68.00

(±)-α-Methylbenzylamine, 100 ml

sc-239163A
100 ml
$89.00