(±)9-HODE (CAS 98524-19-7)

(±)9-HODE, carrying the CAS number 98524-19-7, is a racemic mixture of 9-hydroxyoctadecadienoic acid enantiomers. This compound is an oxidized derivative of linoleic acid, primarily formed via the enzymatic action of lipoxygenases or through non-enzymatic lipid peroxidation processes. In research, (±)9-HODE plays a critical role in investigating the biochemical mechanisms of lipid oxidation products and their impact on cellular functions. This chemical is of particular interest in studies focusing on its ability to modulate signaling pathways related to oxidative stress and inflammatory responses. The presence of hydroxy groups in its structure allows (±)9-HODE to interact with various cellular receptors and enzymes, influencing signal transduction pathways that govern cellular processes such as apoptosis, proliferation, and differentiation. Researchers have utilized (±)9-HODE to explore its effects on lipid signaling cascades and its interactions with proteins involved in cellular defense mechanisms against oxidative damage. By studying this compound, insights into how cells respond to oxidative stress and regulate lipid mediator levels are gained, contributing to a broader understanding of the physiological roles of oxidized fatty acids in maintaining cellular homeostasis and responding to environmental stressors. This research provides foundational knowledge that aids in comprehending the complex networks of lipid-mediated cellular regulation.