Molecular structure of (±)5(6)-EET-d11
(±)5(6)-EET-d11
Alternate Names:
5(6)-EpETrE-d11
Application:
(±)5(6)-EET-d11 is an internal standard of 5(6)-EET bcy GC- or LC-mass spectrometry
Molecular Weight:
331.5
Molecular Formula:
C20H21D11O3
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
(±)5(6)-EET-d11 contains 11 deuterium atoms 16, 16′, 17, 17′, 18, 18′ ,19, 19′ ,20, 20, and 20 positions. It is used as an internal standard for the quantification of (±)5(6)-EET by GC- or LC-mass spectrometry (MS). (±)5(6)-EET is biosynthesized in rat and rabbit liver microsomes by cCYP450.1,2 In neuroendocrine cells, such as the anterior pituitary and pancreatic islet, (±)5(6)-EET has been implicated in the mobilization of Ca2+ and hormone secretion(3,4).
(±)5(6)-EET-d11 References
1 Chacos, N., Falck, J.R., Wixtrom, C., et al. Novel epoxides formed during the liver cytochrome P-450 oxidation of arachidonic acid. Biochem Biophys Res Commun 104 916-922 (1982). 2 Oliw, E.H., Guengerich, F.P., Oates, J.A. Oxygenation of arachidonic acid by hepatic monooxygenases. Isolation and metabolism of four epoxide intermediates. J Biol Chem 257 3771-3781 (1982). 3 Snyder, C., Lattanzio, F., Yadagiri, P., et al. 5,6-Epoxyeicosatrienoic acid mobilizes Ca2+ in anterior pituitary cells. Biochem Biophys Res Commun 139 1188-1194 (1986). 4 Falck, J.R., Manna, S., Moltz, J., et al. Epoxyeicosatrienoic acids stimulate glucagon and insulin release from isolated rat pancreatic islets. Biochem Biophys Res Commun 114 743-749 (1983).Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(±)5(6)-EET-d11, 10 µg | sc-221071 | 10 µg | $196.00 | |||
(±)5(6)-EET-d11, 25 µg | sc-221071A | 25 µg | $465.00 |