Molecular structure of (±)5-HETrE, CAS Number: 88053-46-7
(±)5-HETrE (CAS 88053-46-7)
Application:
(±)5-HETrE is an essential fatty acid analogue of arachidonic acid
CAS Number:
88053-46-7
Molecular Weight:
322.5
Molecular Formula:
C20H34O3
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
(±)5-HETrE is an essential fatty acid analogue of arachidonic acid that is readily converted to leukotriene A3 via the 5-lipoxygenase-leukotriene pathway. Studies suggest that (±)5-HETrE has depressive effects on osteoblast activity. In addition, (±)5-HETrE has a potentiating effect on human platelet aggregation as a result of high levels of (±)5-HETrE in the phospholipids of platelets which cause a higher susceptibility of platelets to thrombin-induced aggregation.
(±)5-HETrE (CAS 88053-46-7) References
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- Integrated analysis of whole blood oxylipin and cytokine responses after bacterial, viral, and T cell stimulation reveals new immune networks. | Villain, E., et al. 2023. iScience. 26: 107422. PMID: 37575177
- Cold-induced changes in plasma signaling lipids are associated with a healthier cardiometabolic profile independently of brown adipose tissue. | Jurado-Fasoli, L., et al. 2024. Cell Rep Med. 5: 101387. PMID: 38262411
- Products derived from 5,8,11-eicosatrienoic acid by the 5-lipoxygenase-leukotriene pathway. | Jakschik, BA., et al. 1983. J Biol Chem. 258: 12797-800. PMID: 6313677
- Potentiating effect of 5,8,11-eicosatrienoic acid on human platelet aggregation. | Lagarde, M., et al. 1983. Lipids. 18: 291-4. PMID: 6408333
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(±)5-HETrE, 50 µg | sc-200948 | 50 µg | $76.00 |