(±)4-HDoHE (CAS 90906-40-4)

(±)4-HDoHE, registered under CAS number 90906-40-4, is a hydroxydocosahexaenoic acid derivative, specifically involving the docosahexaenoic acid (DHA), which is an omega-3 fatty acid primarily found in marine oils like fish oil. This compound features a hydroxyl group at the fourth carbon and includes both enantiomers, as indicated by the (±) notation. In scientific research, (±)4-HDoHE is explored for its potential role in modulating cellular signaling pathways related to inflammation and other cellular functions. As a lipid mediator, it is particularly intriguing due to its interaction with various enzymes and receptors that influence cellular signaling networks. These interactions are pivotal in regulating the synthesis and activity of a range of bioactive molecules, including cytokines and eicosanoids, which are crucial in managing the body′s inflammatory responses. Studies focusing on (±)4-HDoHE aim to delineate its effects on the complex pathways of lipid metabolism and signaling. By understanding how this compound influences these pathways, researchers can gain insights into the broader biological roles of omega-3 fatty acids. Such research is vital for advancing our knowledge of cellular mechanisms that control inflammation, cellular protection, and homeostasis, ultimately contributing to our understanding of how dietary factors can influence cellular health and function.